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US 10,364,208 B2Granted
Oxidative coupling of aryl boron reagents with SP3-carbon nucleophiles, and ambient decarboxylative arylation of malonate half-esters via oxidative catalysis
AssigneeThe Governors of the University of Alberta
InventorsRylan Lundgren, Patrick Moon
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Abstract
Described herein are methods of oxidative coupling of aryl boron reagents with sp3-carbon nucleophiles, and ambient decarboxylative arylation of malonate half-esters via oxidative catalysis.
Claims8
A method for decarboxylative carbonyl α-arylation, comprising:
- reacting
- a. an aryl coupling partner,
- b. a beta-carbonyl carboxylic acid, and
- c. a copper based catalyst
- the reaction taking place at room temperature, exposed to air, thereby creating a carbon-carbon bond.
2 more elements
Dependencies are inferred from the claim text.