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US 10,363,355 B2Granted
System and method for platelet removal during mononuclear cell collection
AssigneeFenwal, Inc.
InventorsJonathan W. Prendergast, Lan T. Nguyen, Katherine N. Radwanski
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Abstract
A method of collecting mononuclear cells, comprising separating whole blood into cellular components and platelets suspended in plasma, separating the platelets suspended in plasma into platelet concentrate and platelet-poor plasma, combining the cellular components with the platelet-poor plasma to form a first mixture, and separating the first mixture into mononuclear cells and at least one component.
Claims20
A method of collecting mononuclear cells, comprising:
- separating whole blood into cellular components and platelet-rich plasma;
- separating the platelet-rich plasma into platelet concentrate and platelet-poor plasma;
- combining the cellular components with the platelet-poor plasma to form a first mixture;
- and
- separating the first mixture into mononuclear cells and at least one component.
2 more elements
An automated system of collecting mononuclear cells, comprising:
- a separator including a controller;
- and
- a disposable fluid circuit configured to work in association with the separator, wherein the controller is configured to control the separator to
- separate whole blood in the disposable fluid circuit into cellular components and platelet-rich plasma,
- separate the platelet-rich plasma into platelet-concentrate and platelet-poor plasma,
- combine the cellular components with the platelet-poor plasma to form a first mixture, and
- separate the first mixture into mononuclear cells and at least one component.
4 more elements
Dependencies are inferred from the claim text.