Method for estimating an amount of analyte in a fluid
AssigneesCommissariat A L'energie Atomique Et Au Energies Alternatives, Avalun
InventorsJean-Guillaume Coutard, Patrick Pouteau, Myriam Laure Cubizolles
Life of this patent
Estimating the term…
Abstract
The invention is a method for estimating the amount of analyte in a fluid sample, and in particular in a bodily fluid. The sample is mixed with a reagent able to form a color indicator in the presence of the analyte. The sample is then illuminated by a light beam produced by a light source; an image sensor forms an image of the beam transmitted by the sample, from which image a concentration of the analyte in the fluid is estimated. The method is intended to be implemented in compact analyzing systems. One targeted application is the determination of the glucose concentration in blood.
Claims15
A method for determining a lysis of particles, the particles lying within a fluid sample, the method comprising:
- mixing the sample with a lysis reagent, the lysis reagent being configured to lyse some particles;
- illuminating the sample using a light source configured to emit light toward the sample;
- acquiring, using an image sensor, an image of light transmitted or reflected by the sample, the image sensor comprising pixels;
- calculating a lysis indicator from the image, the lysis indicator representing a progress of the lysis of particles in the sample;
- and
- calculating a dispersion term representing a dispersion of the intensity of the pixels of the image acquired by the image sensor;
- wherein the lysis indicator is derived from the dispersion term.
A method for determining a lysis of particles, the particles lying within a fluid sample, the method comprising:
- mixing the sample with a lysis reagent, the lysis reagent being configured to lyse some particles;
- illuminating the sample using a light source configured to emit light toward the sample;
- acquiring, using an image sensor, at least two images of light transmitted or reflected by the sample, at two different times respectively, the image sensor comprising pixel;
- calculating, using a processor, a lysis indicator from the image, the lysis indicator representing a progress of the lysis of particles in the sample;
- the method further comprising comparing the two images;
- wherein the lysis indicator is derived from the comparison of the two images.
Dependencies are inferred from the claim text.