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US 10,338,038 B2Granted
Establishing fluidic connections between chromatography components
AssigneeWaters Technologies Corporation
InventorsPeter Kirby, Marcos O. Peroza, Steven D. Trudeau, Ryan Hill, Raymond P. Fisk, Jonathan Belanger, Wade P. Leveille
Life of this patent
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Abstract
A clamp assembly includes a rail configured to receive a first fluidic assembly, and a carriage slidably mounted to the rail and configured to receive a second fluidic assembly. The carriage is operable to establish a first fluid tight seal between the first fluidic assembly and a chromatography column received within the clamp assembly, and to establish a second fluid tight seal between the second fluidic assembly and the chromatography column.
Claims24
A clamp assembly comprising:
- a rail configured to receive a first fluidic assembly;
- and
- a carriage including a carriage body, a lever, a foot displaceably coupled to the carriage body, a hinge about which the lever is configured to rotate when the lever is actuated, and a cam operably attached to the hinge and configured to rotate when the lever is actuated, the cam configured to engage with the foot to displace the foot into engagement with the rail, the carriage being slidably mounted to the rail and configured to receive a second fluidic assembly,
- wherein the foot is configured to selectively engage the rail to inhibit movement of the carriage relative to the rail,
- wherein actuation of the lever is configured:
- to establish a first fluid tight seal between the first fluidic assembly and the chromatography column,
- to establish a second fluid tight seal between the second fluidic assembly and the chromatography column, and
- to displace the foot into engagement with the rail.
5 more elements
A clamp assembly comprising:
- a rail configured to receive a first fluidic assembly;
- and
- a carriage including a carriage body, a lever assembly, and a foot coupled to the carriage body, the carriage being slidably mounted to the rail and configured to receive a second fluidic assembly;
- wherein the foot is configured to move between a first position, in which the foot is clear of the rail to permit movement of the carriage relative to the rail, and a second position, in which the foot engages the rail to inhibit movement of the carriage relative to the rail;
- wherein actuation of the lever assembly is configured to
- move a chromatography column received within the clamp assembly relative to the rail to create a first fluid tight seal between the chromatography column and the first fluidic assembly,
- move the second fluidic assembly relative to the carriage body to create a second fluid tight seal between the second fluidic assembly and the chromatography column, and
- move the foot from the first position to the second position.
5 more elements
A clamp assembly comprising:
- a rail configured to receive a first fluidic assembly;
- and
- a carriage including a carriage body, a lever, an arm coupled to the lever and the carriage body, and a foot coupled to the carriage body, the carriage being slidably mounted to the rail and configured to receive a second fluidic assembly;
- wherein actuation of the lever moves the foot relative to the carriage body between a first position, in which the foot is clear of the rail, to a second position, in which the foot engages the rail and inhibits movement of the carriage relative to the rail;
- wherein actuation of the lever moves a chromatography column received within the clamp assembly relative to the rail to create a first fluid tight seal between the chromatography column and the first fluidic assembly;
- wherein actuation of the lever moves the second fluidic assembly relative to the carriage body to create a second fluid tight seal between the second fluidic assembly and the chromatography column.
3 more elements
Dependencies are inferred from the claim text.