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US 10,337,012 B2Granted
Method and composition for the treatment, prevention, and diagnosis of cancer containing or derived from cancer stem cells
Assignees3-D Matrix, Ltd., National Cancer Center
InventorTakahiro Ochiya
Life of this patent
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Abstract
The invention provides a method and composition for the treatment, prevention, and diagnosis of cancer containing or derived from cancer stem cells.
Claims12
A method of treating a cancer containing or derived from cancer stem cells comprising a step of administering an siRNA-carrier complex comprising an siRNA against ribophorin II (RPN2) and a transport carrier to a subject in need thereof, wherein the cancer stem cells have a mutated p53 gene, and wherein the siRNA interferes with RPN2 gene expression in an in vitro assay.
Dependencies are inferred from the claim text.