Method of producing nylon
AssigneeEvonik Degussa GmbH
InventorsThomas Haas, Eva-Maria Eckl, Simon Beck
Life of this patent
Estimating the term…
Abstract
There is provided a method of producing aminohexanoic acid and/or aminohexanoic acid ester from synthesis gas, the method comprising: A. contacting the synthesis gas with at least one bacteria capable of carrying out the Wood-Ljungdahl pathway and the ethanol-carboxylate fermentation to produce hexanoic acid; and B. contacting the hexanoic acid with a genetically modified cell to produce aminohexanoic acid and/or aminohexanoic acid ester, wherein the genetically modified cell has an increased activity, in comparison with its wild type, of alkane monooxygenase, alcohol dehydrogenase, and ω-transaminase.
Claims15
A method of producing 6-aminohexanoic acid and/or 6-aminohexanoic acid ester from synthesis gas, the method comprising:
- A. contacting the synthesis gas with:
- (i) at least one bacteria capable of carrying out both the Wood-Ljungdahl pathway and the ethanol-carboxylate fermentation to produce hexanoic acid;
- or
- (ii) at least one bacteria capable of carrying out the Wood-Ljungdahl pathway and at least a second bacteria capable of carrying out ethanol-carboxylate fermentation to produce hexanoic acid;
- and
- B. contacting the hexanoic acid with a genetically modified cell to produce 6-aminohexanoic acid and/or 6-aminohexanoic acid ester, wherein, in comparison with its wild type, the genetically modified cell has increased activity, of all three enzymes:
- alkane monooxygenase, alcohol dehydrogenase, and ω-transaminase, wherein the alcohol dehydrogenase is encoded by an AlkJ gene (EC 1.1.99-2).
Dependencies are inferred from the claim text.