Electric pulse generation systems using capacitive coupling
AssigneeGeneral Electric Company
InventorsAntonio Caiafa, Vasile Bogdan Neculaes, Allen Lawrence Garner, Andrew Soliz Torres
Life of this patent
Estimating the term…
Abstract
In accordance with the present disclosure, exposure of a sample to one or more electric pulses via capacitive coupling is described. In certain embodiments, the sample may be a biological sample to be treated or modified using the pulsed electric fields. In certain embodiments, the electric pulses may be delivered to a load using capacitive coupling. In other embodiments, the electric pulses may be bipolar pulses.
Claims17
An electric pulse generation system comprising:
- a sample holder comprising two electrodes wherein the sample holder is configured to electrically couple the two electrodes to a sample container disposed in the sample holder;
- pulse generating circuitry configured to generate an electrical pulse between the two electrodes;
- control circuitry configured to cause the pulse generating circuitry to generate the electrical pulse to deliver a pulse to the sample container disposed in the sample holder;
- and
- a capacitor disposed in series with the pulse generating circuitry and the two electrodes during the generation of the electrical pulse between the two electrodes.
An electric pulse generation system comprising:
- a sample holder comprising two electrodes disposed on opposite sides of the sample holder, wherein the sample holder is configured to receive a sample container;
- pulse generating circuitry configured to supply a pulse between the electrodes;
- a first resistive path that directly couples the pulse generating circuitry and the two electrodes;
- a second resistive path that couples the pulse generating circuitry and the two electrodes through a capacitive element disposed in series with the two electrodes and the pulse generating circuitry;
- and
- switching circuitry configured to select between the first and the second resistive path.
A method to operate an electric pulse generation system, the method comprising:
- placing a sample in a sample container;
- placing the sample container in a sample holder comprising two electrodes, wherein the sample in the sample container is electrically coupled to the two electrodes;
- and
- causing a pulse generating circuitry to deliver an electric pulse signal to the sample in the sample container via a circuit that comprises:
- the pulse generating circuitry;
- the two electrodes;
- and
- a capacitor arranged in series with the two electrodes and the pulse generating circuitry during the delivery of the electric pulse signal.
Dependencies are inferred from the claim text.