Live attenuated Arkansas serotype infectious bronchitis virus vaccine
AssigneeUniversity of Georgia Research Foundation, Inc.
InventorsBrian J. Jordan, Mark W. Jackwood
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Abstract
Attenuated isolates of the Arkansas serotype of infectious bronchitis virus (IBV), including the IBV isolate ArkGA p60 deposited at the ATCC under Patent Designation PTA-123783, and compositions thereof are presented. Methods for administering the isolates or compositions as vaccines to the prevent virulent IBV infection in birds of the order Galliformes are also presented.
Claims23
An infectious bronchitis virus (IBV) isolate, wherein the IBV isolate comprises the IBV isolate ArkGA p60 deposited at the ATCC under Patent Designation PTA-123783.
An attenuated infectious bronchitis virus (IBV) isolate of the Arkansas serotype, the attenuated IBV isolate comprising an S1 glycoprotein subunit comprising an amino acid sequence comprising at least 95% sequence identity to SEQ ID NO:
- 2, and wherein the S1 glycoprotein subunit comprises a histidine residue at amino acid position 386.
An isolated S1 polypeptide comprising at least 95% identity to SEQ ID NO:
- 2 and wherein the S1 polypeptide comprises a histidine residue at amino acid position 386.
Dependencies are inferred from the claim text.