Composition and system for separating and detecting alpha-fetoprotein variant and use thereof
AssigneeBeijing Hotgen Biotech Co., Ltd.
InventorsHaifeng Luo, Boan Li, Changqing Lin
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Abstract
Disclosed are a composition and system for separating and detecting an alpha-fetoprotein variant, comprising a separation reagent and a detection reagent; a system for separating and detecting an alpha-fetoprotein variant and a use thereof; and a kit for separating and detecting the alpha-fetoprotein variant. By means of the composition and system for separating and detecting the alpha-fetoprotein variant, and the use thereof, primary liver cancer can be indicated early on, the sensitivity is high, and the method is rapid, simple and automated.
Claims13
A separation and detection kit for an alpha-fetoprotein variant AFP-L3, comprising a separation reagent, a detection reagent and a reaction plate, wherein
- the separation reagent comprises a magnetic particle coupling a lectin, and an eluent, wherein the surface of the magnetic particle coupling the lectin is covered with an epoxy resin, the magnetic particle coupling the lectin specifically binds to the alpha-fetoprotein variant AFP-L3 in a sample;
- the detection reagent comprises a magnetic particle coated with an anti-alpha-fetoprotein antibody and an enzyme-labeled anti-alpha-fetoprotein antibody;
- and the reaction plate is in a form of a card and comprises a reagent tank and a reaction well.
Dependencies are inferred from the claim text.