Indoline compounds as granzyme B inhibitors

A compound having Formula (III):

• or a stereoisomer, tautomer, or pharmaceutically acceptable salt thereof, wherein:
• R1a is tetrazole or triazole;
• R3 is H or C1-C4 alkyl substituted with a carboxylic acid or carboxylate group;
• R4 is C3-C6 cycloalkyl or C1-C6 alkyl optionally substituted with hydroxyl or C1-C6 alkoxy;
• and
• R10 is —(CH2)n—CO2H, wherein n is 2, 3, 4, 5, or 6,
• optionally wherein one or more single methylene carbons are substituted with a fluoro, hydroxy, amino, C1-C3 alkyl, or C6-C10 aryl group,
• optionally wherein one or more single methylene carbons are substituted with two fluoro or C1-C3 alkyl groups,
• optionally wherein one or more single methylene carbons are substituted with two alkyl groups that taken together with the carbon to which they are attached form a 3, 4, 5, or 6-membered carbocyclic ring, or
• optionally wherein adjacent carbon atoms from an unsaturated carbon-carbon bond or taken together form a benzene ring;
• or
• R10 is
• wherein n is 1, 2, 3, or 4, and
• optionally, for n=3 or 4, wherein adjacent carbon atoms from an unsaturated carbon-carbon bond.