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AssigneeQianjin Pharmaceutical Co., Ltd.
InventorsPeng Zhang, Kaifeng Peng, Yun Gong, Fujun Li, Nifu Liu, Bohou Xia, Limei Lin
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The present invention provides a phenylpropanoid compound and a preparation method and use thereof. The phenylpropanoid compound has a structural formula shown as formula (I), and the pharmaceutically acceptable salt has a structural formula shown as formula (II), formula (III), formula (IV), or formula (V). The phenylpropanoid compound and the pharmaceutically acceptable salt thereof have an effect on inhibiting a content of an inflammatory cytokine NO and an expression of an inflammatory cytokine TNF-α, have an effect on inhibiting a hydroxyl radical (—OH), thereby have anti-inflammatory and antioxidant activities, and has a good application prospect in preparing of a medicine for treating an inflammatory disease related to the above factors, such as cervicitis, endometritis, pelvic inflammatory disease, mastitis, sphagitis and/or arthritis.
A pharmaceutically acceptable salt of a phenylpropanoid compound, wherein the pharmaceutically acceptable salt has a structural formula shown as formula (II), formula (III), formula (IV), or formula (V):
A preparation method of a phenylpropanoid compound, wherein the preparation method comprises steps as follows:
A method of using a phenylpropanoid compound and a pharmaceutically acceptable salt thereof for treating an inflammatory disease, the method comprises:
Dependencies are inferred from the claim text.