Process for purifying long chain amino acids
AssigneeVitaworks IP, LLC
InventorsSongzhou Hu, William S. Hu
Life of this patent
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Abstract
There is disclosed a process for the purification of long chain amino acids by recrystallization in an aqueous solution of organic carboxylic acid in the absence or presence of solvent, comprising: (1) dissolving a long chain amino acid in an aqueous solution of organic carboxylic acid by heating; (2) cooling the solution of step (1) to crystallize the long chain amino acid; and (3) recovering the long chain amino acid of step (2) by means of solid-liquid separation.
Claims20
A process for the purification of an isomeric mixture of long chain amino acids (IIa) and (IIb) or an isomeric mixture of long chain amino acids (IIa) and (IIc) of the following structures:
- wherein m is an integer from 4 to 20, by recrystallization in an aqueous solution of organic carboxylic acid in the absence or presence of solvent, comprising:
- (1) dissolving an isomeric mixture of long chain amino acids in an aqueous solution of organic carboxylic acid by heating;
- (2) cooling the solution of step (1) to crystallize the isomeric mixture of long chain amino acids;
- and
- (3) recovering the isomeric mixture of long chain amino acid of step (2) by means of solid-liquid separation.
A process for the purification of an isomeric mixture of long chain amino acids (IIa) and (IIb) or an isomeric mixture of long chain amino acids (IIa) and (IIc) of the following structures:
- wherein m is an integer from 4 to 20, by forming an acid salt in an aqueous solution of inorganic acid, comprising:
- (1) dissolving an isomeric mixture of long chain amino acids in an aqueous solution of inorganic acid by heating;
- (2) treating the solution of step (1) with activated carbon, or filter aid, or an extractant solvent;
- (3) cooling the solution of step (2) to crystallize the acid salt of the long chain amino acid;
- (4) separating the acid salt of step (3) by means of solid-liquid separation;
- and
- (5) neutralizing the acid salt of step (4) with a basic agent to yield the isomeric mixture of long chain amino acids.
A process for the purification of an isomeric mixture of long chain amino acids (IIa) and (IIb) or an isomeric mixture of long chain amino acids (IIa) and (IIc) of the following structure:
- wherein m is an integer from 4 to 20, by recrystallization in an aqueous solution of inorganic acid, comprising:
- (1) dissolving an isomeric mixture of long chain amino acids in an aqueous solution of inorganic acid by heating to form an acid salt;
- (2) treating the solution of step (1) with activated carbon, or filter aid, or an extractant solvent;
- and
- (3) neutralizing the solution of step (2) with a basic agent to yield the isomeric mixture of long chain amino acids.
Dependencies are inferred from the claim text.