Patch-sized fluid delivery systems and methods

An apparatus comprising:

• a disposable portion comprising a substrate having flexible membrane material thereon and incorporating therein a fluid channel from a reservoir port to a cannula port and comprising at least one region exposed to the flexible membrane material, wherein the at least one region is a valve region;
• and
• a reusable portion comprising a control assembly having a mechanical assembly that interacts with the at least one region through the membrane material to pump fluid through the fluid channel, the mechanical assembly including a valve actuator operating on the valve region;
• wherein the substrate includes a dispensing chamber formed in the fluid channel of the substrate, such chamber bounded by flexible membrane material forming a dispensing chamber membrane;
• wherein the control assembly includes a fluid sensor in communication with the dispensing chamber for measuring fluid flow through the dispensing chamber:
• wherein the fluid sensor is an acoustic volume sensor;
• and
• wherein the acoustic volume sensor includes a loudspeaker, and wherein the loudspeaker is used by the control assembly for both acoustic volume sensing and audible alarm generation.

An apparatus comprising:

• a disposable portion comprising a substrate having flexible membrane material thereon and incorporating therein a fluid channel from a reservoir port to a cannula port and comprising at least one region exposed to the flexible membrane material, wherein the at least one region is a valve region;
• and
• a reusable portion comprising a control assembly having a mechanical assembly that interacts with the at least one region through the membrane material to pump fluid through the fluid channel, the mechanical assembly including a valve actuator operating on the valve region;
• wherein the substrate includes a dispensing chamber formed in the fluid channel of the substrate, such chamber bounded by flexible membrane material forming a dispensing chamber membrane;
• wherein the control assembly includes a fluid sensor in communication with the dispensing chamber for measuring fluid flow through the dispensing chamber:
• wherein the fluid sensor is an acoustic volume sensor;
• and
• wherein the acoustic volume sensor includes a microphone, and wherein the microphone is used by the control assembly for both acoustic volume sensing and monitoring pump operation.

An apparatus comprising:

• a disposable portion comprising a substrate having flexible membrane material thereon and incorporating therein a fluid channel from a reservoir port to a cannula port and comprising at least one region exposed to the flexible membrane material, wherein the at least one region is a valve region;
• and
• a reusable portion comprising a control assembly having a mechanical assembly that interacts with the at least one region through the membrane material to pump fluid through the fluid channel, the mechanical assembly including a valve actuator operating on the valve region;
• wherein the substrate and the flexible membrane material of the disposable portion constitute a fluidic assembly, and wherein the disposable portion further includes a disposable base into which the fluidic assembly fits, the apparatus further comprising an adhesive pad coupled to a bottom of the disposable base.

An apparatus comprising:

• a disposable portion comprising a substrate having flexible membrane material thereon and incorporating therein a fluid channel from a reservoir port to a cannula port and comprising at least one region exposed to the flexible membrane material, wherein the at least one region is a valve region;
• a reusable portion comprising a control assembly having a mechanical assembly that interacts with the at least one region through the membrane material to pump fluid through the fluid channel, the mechanical assembly including a valve actuator operating on the valve region;
• and
• a temperature sensor disposed in one of the reusable portion and the disposable portion for providing temperature information to the control assembly.