Implant comprising oxidized cellulose and method for preparing such an implant
AssigneeSofradim Production
InventorsAurelie Serrero, Robert Vestberg, Suzelei Montanari
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Abstract
The present invention relates to an implant (10) comprising: —a substrate (1) the surface of which comprising oxidized cellulose, said oxidized cellulose having a degree of oxidation ranging from 0.0 to 1, and —a multilayer coating covering said substrate, said multilayer coating comprising at least a first layer (2) adjacent said substrate, said first layer being formed of chitosan, and a second layer (3) adjacent said first layer, said second layer being formed of oxidized cellulose having a degree of oxidation ranging from 0.5 to 1. The invention further relates to a method for preparing such an implant.
Claims19
A method for preparing an implant comprising:
- contacting a substrate having a surface including at least oxidized cellulose, said oxidized cellulose having a degree of oxidation ranging from 0.5 to 1, with a solution of chitosan to form a first layer adjacent said surface of said substrate;
- and
- covering the first layer with a solution of oxidized cellulose having a degree of oxidation from 0.5 to 1 to form a second layer adjacent said first layer.
A method for preparing an implant comprising:
- i) covering a surface of a substrate with a solution of chitosan to form a first layer on the surface of the substrate, said surface of said substrate comprising at least oxidized cellulose having a degree of oxidation ranging from 0.5 to 1;
- ii) covering said first layer on said surface of said substrate with a solution of oxidized cellulose to form a second layer adjacent said first layer;
- and
- iii) optionally repeating i) and ii) as many times as desired.
Dependencies are inferred from the claim text.