Device and method for ultra-high temperature sterilization of an emulsion
AssigneePierre Fabre Dermo-Cosmetique
InventorsJean-Claude Delaunay, Franck Legendre
Life of this patent
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Abstract
A method for high temperature sterilization of an emulsion, in particular a dermocosmetic preparation. The method includes the steps of gradually pre-heating, performing ultra-high temperature sterilization and gradually cooling the emulsion. The emulsion is heated up to a pre-heating temperature, which is the temperature of the emulsion at the stability limit. Ultra-high temperature sterilization is performed by infusion of the pre-heated emulsion by heating the emulsion up to a sterilization temperature, maintaining the emulsion at the sterilization temperature, and cooling the emulsion under a vacuum at an end-of-sterilization temperature. The emulsion is gradually cooled with agitation to a storage temperature.
Claims6
A device for high temperature sterilization of a dermocosmetic preparation, comprising:
- a plurality of scraped surface heat exchangers to gradually pre-heat the dermocosmetic preparation in a form of an emulsion up to a pre-heating temperature, and to gradually cool said emulsion;
- an UHT infusion sterilizer to perform ultra-high temperature sterilization by infusion of said emulsion after it is pre-heated by further heating said emulsion up to a sterilization temperature, maintaining said emulsion at the sterilization temperature;
- and cooling said emulsion under vacuum at an end of the sterilization temperature;
- two cooling scraped surface heat exchangers to gradually cool said emulsion in plateaus with a maximum change in temperature between two cooling plateaus of 15K or 15° C., the temperature of the two cooling scraped surface heat exchangers are set to the two cooling plateaus;
- a mixer at an outlet of the UHT infusion sterilizer and before an inlet of the two cooling scraped surface heat exchangers to treat said emulsion by shearing;
- and
- a bypassing device to prevent passage of the sterilized emulsion into the mixer.
A device for high temperature sterilization of a dermocosmetic preparation, comprising:
- a plurality of scraped surface heat exchangers to gradually pre-heat the dermocosmetic preparation in a form of an emulsion up to a pre-heating temperature, and to gradually cool said emulsion;
- an UHT infusion sterilizer to perform ultra-high temperature sterilization by infusion of said emulsion after it is pre-heated by further heating said emulsion up to a sterilization temperature, maintaining said emulsion at the sterilization temperature;
- and cooling said emulsion under vacuum at an end of the sterilization temperature;
- two cooling scraped surface heat exchangers to gradually cool said emulsion in plateaus with a maximum change in temperature between two cooling plateaus of 15K or 15° C., the temperature of the two cooling scraped surface heat exchangers are set to the two cooling plateaus;
- a mixer at an outlet of the last cooling scraped surface heat exchanger of the two cooling scraped surface heat exchangers;
- and
- a bypassing device to prevent passage of the sterilized emulsion into the mixer.
Dependencies are inferred from the claim text.