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US 10,328,154 B2Granted
Topical compositions for improved delivery of active agents
AssigneeBUFFERAD Illinois Inc.
InventorsXiaoyan Xu, Wen Yang, Nguyet Le, Jerry Z. Zhang
Life of this patent
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Abstract
A topical composition and methods of making the composition is disclosed. The composition may comprise an ointment base, C11-C40 alcohols or acids, and a polymer. The ointment base may be in an amount of at least about 50% of the topical composition by weight. The polymer may be substantially soluble in the ointment base.
Claims23
A topical composition, comprising:
- an ointment base in an amount of at least about 50% of the topical composition by weight;
- C11-C40 alcohols or C11-C40 acids, or combinations thereof;
- and
- a substantially soluble polymer in the ointment base.
1 more element
A topical composition, comprising:
- (a) a therapeutically effective amount of an active agent;
- (b) a petrolatum ointment base;
- (c) C11-C40 alcohols or C11-C40 acids, or combinations thereof;
- and
- (d) a substantially soluble polymer in the petrolatum ointment base, wherein a combination of alcohols or acids with the polymer enhances a release of the active agent.
2 more elements
A process for preparing an ointment composition comprising:
- (a) dissolving or suspending a therapeutically effective amount of an active agent in an ointment base;
- (b) mixing C11-C40 alcohols or C11-C40 acids, or combinations thereof;
- and
- (c) mixing a polymer wherein the polymer is substantially soluble in the ointment base.
1 more element
Dependencies are inferred from the claim text.