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AssigneesJeonnam Bioindustry Foundation, Yungjin Pharmaceutical Co., Ltd.
InventorsChul Yung Choi, Sang O Pan, Hee Jin Seol, Gyu Ok Lee, Wook Jin Jang, Hee Sook Kim, Jae Yong Kim, HuWon Kang, Dong Wook Lee, Sun Oh Kim, Jae Gap Kim, JoonYung Park
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The present invention relates to a composition for promoting osteoblast or cartilage cell differentiation. More particularly, the present invention relates to a composition, which includes stauntonia hexaphylla leaf extract that may be safely used without toxicity and side effects by using a natural ingredient, for promoting bone (tissue) formation to be used for suppressing and treating bone and cartilage tissue damage. A pharmaceutical composition including the stauntonia hexaphylla leaf extract according to the present invention as an active ingredient may be used as a medicine for periodontitis or osteoporosis to treat or prevent periodontitis or osteoporosis.
A pharmaceutical composition for promoting bone or cartilage tissue formation consisting of a stauntonia hexaphylla fraction as an active ingredient that is made by extracting stauntonia hexaphylla leaf by boiling in water at 110° C. for 4 hours, separating into hexane soluble and insoluble layer, and using ethyl acetate to fractionate the hexane insoluble layer;
Dependencies are inferred from the claim text.