Medical treatment composition comprising mammalian dental pulp stem cells
OwnerRay C. Wasielewskiinventor
Life of this patent
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Abstract
A medical implant comprising in components from a tooth and stem cells harvested from at least one tooth. Pluripotent stem cells, other cells, and biologic constituents of the dental pulp may be harvested from the dental pulp of mammalian teeth, such as unerupted third molars in humans. After the stem cells are removed and isolated from the other teeth tissue, the hard tooth may be ground into a base material for the manufacture of a porous matrix into which the pluripotent stem cells, other cells, and biologic constituents of the dental pulp can be added. Additionally, soft tissue from the harvested tooth may be used as a carrier scaffold for soft tissue applications such as meniscal or cartilage repair.
Claims20
A medical treatment composition comprising:
- a dental pulp suspension including viable mammalian dental pulp stem cells, mammalian dental pulp proteins, and extracellular matrix proteins, wherein the suspension has not been digested by collagenase and the stem cells have not been cultured;
- and
- a non-naturally occurring cryoprotectant, the cryoprotectant being dimethyl sulfoxide;
- wherein the composition is in a form that is safe for injection into pathologic or injured tissue.
A medical treatment composition comprising:
- a dental pulp that has been filtered to provide a particulate form including viable mammalian dental pulp stem cells, mammalian dental pulp proteins, and extracellular matrix proteins;
- and
- a non-naturally occurring cryoprotectant;
- wherein the composition is in a form that is suitable for injection into pathologic or injured tissue.
A medical treatment composition comprising:
- a mechanically disrupted dental pulp suspension including viable mammalian dental pulp stem cells, mammalian dental pulp proteins, and extracellular matrix proteins, wherein the mechanically disrupted dental pulp is achieved by grinding dental pulp;
- and
- a non-naturally occurring cryoprotectant;
- wherein the composition is in a form that is safe for injection into pathologic or injured tissue.
Dependencies are inferred from the claim text.