Inactivation of papillomavirus

An anal treatment apparatus for treatment of early papillomavirus infection of an anal canal of a human body, comprising:

• a stem adapted for insertion along the anal canal, where the anal canal comprises an inner end and an opposing outer end, and further comprises an anorectal ring at the inner end and an anal verge at the outer end;
• an upper occlusion device and a lower occlusion device;
• wherein the upper occlusion device is a fluid expandable balloon carried by the stem that when expanded can occlude the anorectal ring at the inner end of the anal canal;
• wherein the lower occlusion device is a conical plug that can occlude the anal verge at the outer end of the anal canal;
• whereby the fluid expandable balloon when expanded and the conical plug are spaced and dimensioned to effectively engage and occlude the anorectal ring and anal verge, respectively, whereby to define a treatment cavity in the anal canal about the stem;
• a passage in the stem that can deliver fluid to the balloon to expand the balloon;
• and
• another passage in the stem that can deliver to the treatment cavity an effective amount of an agent for inactivation of papillomavirus for application to the surfaces of the anal canal bounding the treatment cavity.