Stable amorphous calcium carbonate comprising synthetic phosphorylated peptides
AssigneeAmorphical Ltd.
InventorsShmuel Bentov, Amir Sagi, Amir Berman, Assaf Shechter
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Abstract
Provided are compositions containing amorphous calcium carbonate (ACC), and at least one phosphorylated peptide which stabilizes the amorphous form of said calcium carbonate. Particularly, the peptide can be selected from crustacean proteins, also provided by the invention, namely GAP65, GAP22, GAP21, and GAP12 (also indicated herein as GAP10). The compositions are useful in pharmaceutical and nutraceutical formulations.
Claims11
A method of treating a disease or condition comprising administering to a subject in need thereof a pharmaceutical composition consisting of amorphous calcium carbonate (ACC), phosphorylated peptides having amino acid sequence SEQ ID NO:1 or a sequence homologous thereto at least by 90%, and optionally an additional compound selected from the group consisting of:
- fillers, solvents, and combinations thereof.
Dependencies are inferred from the claim text.