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US 10,328,052 B2Granted
D-proline derivatives as SAP depleting agent
AssigneeGlaxoSmithKline Intellectual Property Development Limited
InventorsAlexis Denis, Olivier Mirguet, Jérôme Toum
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Abstract
The present invention relates to the compound ((2R,2′R)-bis(((tetrahydro-2H-pyran-4-carbonyl)oxy)methyl) 1,1′-adipoylbis(pyrrolidine-2-carboxylate), pharmaceutical compositions comprising the same and the use of the same for treatment of diseases or disorders wherein depletion of serum amyloid P component (SAP) would be beneficial, including amyloidosis, Alzheimer's disease, type 2 diabetes mellitus and osteoarthritis.
Claims20
A compound which is:
Dependencies are inferred from the claim text.