Co-crystals of substituted glycine and uses thereof
AssigneeSyneuRx International (Taiwan) Corp.
InventorsGuochuan Emil Tsai, Ching-Cheng Wang, Tien-Lan Hsieh
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Abstract
The present disclosure provides co-crystals of a substituted glycine compound and a co-former compound of Formula (I): compositions comprising such, and uses thereof in treating and/or reducing the risk for a neuropsychiatric disorder (e.g., schizophrenia, psychotic disorders, depressive disorders, suicidal ideation and/or behavior, obsessive compulsive disorder or Alzheimer's disease). Also provided herein are methods for preparing the co-crystals.
Claims17
A co-crystal of a substituted glycine compound and a co-former, wherein the substituted glycine compound is N-methylglycine or N-dimethylglycine, and wherein the co-former is a compound of Formula (IB):
- in which
- A and B are each independently H,
- W is O;
- X is H;
- Z is OH;
- C2C1 are C2═C1;
- wherein the molecular ratio between the substituted glycine compound and the co-former in the co-crystal ranges from 6:1 to 1:1.
Dependencies are inferred from the claim text.