Ophthalmic emulsion

An ophthalmic emulsion, the emulsion comprising:

• water forming an aqueous phase;
• oil forming an oil phase;
• a hydrophilic surfactant, wherein the hydrophilic surfactant is polyoxyethylene-40-stearate;
• a hydrophobic surfactant, wherein the hydrophobic surfactant is a sorbitan tristearate;
• a charged phospholipid;
• wherein the charged phospholipid is an anionic phospholipid named dimyristoyl phosphatidylglycerol and wherein the phospholipid is present in the emulsion in a concentration from 0.05 to 7.0 percent by weight
• borate;
• a mucoadhesive galactomannan polymer;
• and
• a preservative, wherein the emulsion is free of a benzalkonium chloride,
• wherein:
• i. the oil phase is in droplets within the aqueous phase and the droplets have an average diameter that is no greater than about 1000 nm, but is at least 10 nm, wherein the average diameter is corresponding to 90% of the cumulative undersize distribution by volume measured using a Microtrac S3500 Particle Size Analyzer (Software Version 10.3.1);
• and
• ii. the borate and galactomannan polymer cooperatively act to form a gel upon instillation of the emulsion in an eye of an individual.