Prebiotic oral care methods using a saccharide
AssigneeColgate-Palmolive Company
InventorsHans Stettler, Wim Teughels, Marc Quirynen, Nico Boon
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Abstract
The disclosure relates to methods of enhancing beneficial oral bacteria and decreasing harmful oral bacteria comprising administering oral care compositions comprising a saccharide prebiotic, e.g., selected from D-turanose, D-melezitose, D-lactitol, myoinositol, and N-acetyl-D-mannosamine; and oral care compositions for use in such methods. The disclosure also relates to methods of using prebiotic oral care compositions, methods of screening, and methods of manufacture.
Claims14
A method of cleaning tooth enamel comprising contacting the dental surfaces in a subject with a toothpaste composition without intentional ingestion of the toothpaste composition, wherein the toothpaste composition comprises all of the following ingredients:
- N-acetyl-D-mannosamine in an amount of 0.1% to 5% by weight of the composition;
- water;
- an abrasive for removing debris and surface stains;
- a surfactant;
- a humectant;
- a thickener;
- a flavoring;
- wherein the N-acetyl-D-mannosamine promotes the growth, metabolic activity, or colonization of a bacteria having beneficial effects on oral health selected from the group consisting of Streptococcus mitis, Streptococcus sanguinis, Veillonella parvula, Streptococcus gordonii, and Actinomyces naeslundii, relative to growth, metabolic activity or colonization of pathogenic oral bacteria.
Dependencies are inferred from the claim text.