Functional gain measurement technique and representation

A method for determining improvement of a physiological property after a therapeutic procedure, the method comprising:

• obtaining, prior to conducting the therapeutic procedure, first pressure measurements using a pressure sensor disposed at a distal portion of an intravascular pressure-sensing guidewire positioned within a vessel of a patient;
• determining, at a computer in communication with the intravascular pressure-sensing guidewire and prior to conducting the therapeutic procedure, a baseline quantity of a physiological property associated with the vessel, wherein the physiological property comprises a pressure ratio calculated using the first pressure measurements;
• conducting the therapeutic procedure to treat the vessel;
• obtaining, after conducting the therapeutic procedure, second pressure measurements using the pressure sensor of the intravascular pressure-sensing guidewire positioned within the vessel;
• determining, at the computer and after conducting the therapeutic procedure, a post-therapy quantity of the physiological property based on the second pressure measurements;
• comparing, at the computer, the post-therapy quantity to the baseline quantity;
• calculating, at the computer based on the comparison of the post-therapy quantity to the baseline quantity, a functional gain of the physiological property as a result of the therapeutic procedure;
• and
• outputting, to a display in communication with the computer, a visual representation of the comparing, wherein the visual representation of the comparing comprises displaying:
• a numerical value associated with the functional gain;
• at least one of a numerical value associated with the baseline quantity or a numerical value associated with the post-therapy quantity;
• and
• a visual rendering of the vessel that includes an indication of at least one of the baseline quantity or the post-therapy quantity at a corresponding location of the visual rendering of the vessel.