Method and system for microbiome-derived characterization, diagnostics and therapeutics for conditions associated with functional features

A method for characterizing a gastric cancer condition, the method comprising:

• receiving an aggregate set of samples from a population of subjects, the aggregate set of samples comprising at least one sample associated with the gastric cancer condition;
• for the aggregate set of samples:
• determining microorganism nucleic acid sequences, comprising:
• selecting a set of primers for nucleic acid sequences,
• amplifying nucleic acid material from the aggregate set of samples based on the set of primers;
• and
• determining alignments of the microorganism nucleic acid sequences to reference sequences;
• generating a microbiome feature dataset for the population of subjects based upon the alignments;
• generating a characterization model of the gastric cancer condition from the microbiome feature dataset;
• based upon the characterization model, generating a therapy model that determines a therapy for correcting the gastric cancer condition;
• and
• providing the therapy to a subject diagnosed with the gastric cancer condition based upon the characterization model and the therapy model.