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US 10,316,337 B2Granted
Genetically engineered bacterium for the production of isobutylene
AssigneeLanzatech New Zealand Limited
InventorsMichael Koepke, Rasmus Overgaard Jensen
Life of this patent
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Abstract
The invention relates to a genetically engineered bacterium having an enzyme that converts 3-hydroxyisovaleryl-CoA to 3-hydroxyisovalerate and an enzyme that converts 3-hydroxyisovalerate to isobutylene. Typically, the bacterium is capable of producing isobutylene from a gaseous substrate containing CO, CO2, and/or H2, such as syngas or an industrial waste gas.
Claims11
A genetically engineered C1-fixing bacterium comprising:
- (a) an enzyme that converts 3-hydroxyisovaleryl-CoA to 3-hydroxyisovalerate and
- (b) an enzyme that converts 3-hydroxyisovalerate to isobutylene,
- wherein at least one of the enzymes is exogenous to the bacterium.
Dependencies are inferred from the claim text.