# US 10,310,041 B2 · Method and magnetic resonance apparatus for automatic assignment of a spin species to a combination image > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,310,041 B2 - Document ID: US10310041B2 - Status: Granted - Kind: B2 - Application number: 15/272,724 - Filed: 2016-09-22 - Published: 2017-03-23 - Granted: 2019-06-04 - Earliest claimed: 2015-09-22 - Assignees: Siemens Healthcare GmbH - Applicants: Siemens Healthcare GmbH - Inventors: Matthias Fenchel; Marcel Dominik Nickel - Web page: https://patentgrep.com/patent/US10310041B2 ## CPC - G01R 33/5608: {Data processing and visualization specially adapted for MR, e.g. for feature analysis and pattern recognition on the basis of measured MR data, segmentation of measured MR data, edge contour detection on the basis of measured MR data, for enhancing measured MR data in terms of signal-to-noise ratio by means of noise filtering or apodization, for enhancing measured MR data in terms of resolution by means for deblurring, windowing, zero filling, or generation of gray-scaled images, colour-coded images or images displaying vectors instead of pixels (image data processing or generation, in general G06T)} - G01R 33/4828: {Resolving the MR signals of different chemical species, e.g. water-fat imaging} - G06N 20/00: Machine learning - G01R: MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES (indicating correct tuning of resonant circuits H03J3/12) - G06N: COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS ## Abstract In a method and apparatus for the automatic assignment of at least one combination image of an examination object to a spin species represented in the combination image, relationships, which were determined from an existing database and which relate to the assignment of spin species to combination images, are loaded into a computer. At least two MR datasets at one of at least two echo times in each case following an excitation by means of a multi-contrast measurement are supplied to the computer. At least one combination image is determined in the computer from the at least two MR datasets. The spin species represented in the at least one combination image are assigned in the computer on the basis of the loaded relationships. By using relationships determined from an existing database, an automatic unambiguous global assignment of the correct spin species is enabled. ## Claims ### Claim 1 A method for automatic assignment of at least one magnetic resonance combination image of an examination subject to a magnetic resonance spin species represented in the combination image, comprising: loading predetermined relationships, determined from existing databases, into a computer that define assignment of magnetic resonance spin species to magnetic resonance combination images; operating a magnetic resonance data acquisition scanner to execute a multi-contrast magnetic resonance data acquisition measurement in which at least two echo times are produced, and acquiring at least two magnetic resonance datasets respectively during said at least two echo times; providing said magnetic resonance datasets to said computer and reconstructing at least one combination image from said at least two magnetic resonance datasets; in said computer, using the loaded relationships to assign spin species represented in said determined at least one combination image to respective magnetic resonance spin species; and making an electronic signal representing the assignment of the respective magnetic resonance spin species available from the computer in electronic form. ### Claim 2 (depends on 1) A method as claimed in claim 1 comprising supplementing said existing database with said determined assignment of the respective spin species in the determined at least one combination image, thereby obtaining a supplemented database, and making the supplemented database available for a subsequent automatic assignment of respective magnetic resonance spin species in said computer. ### Claim 3 (depends on 1) A method as claimed in claim 1 comprising, in said computer, defining a probability that the determined assignment of the respective magnetic resonance spin species to said reconstructed combination image is correct. ### Claim 4 (depends on 3) A method as claimed in claim 3 comprising presenting a visual representation of said probability at a display screen in communication with said computer. ### Claim 5 A method for determining relationships of respective magnetic resonance spin species to each other for assigning a respective magnetic resonance spin species to a magnetic resonance combination image reconstructed from at least two magnetic resonance datasets acquired respectively at different echo times of a multi-contrast magnetic resonance data acquisition sequence, wherein only one spin species is represented in said reconstructed combination image, said method comprising: loading a database into a computer that comprises stored designations of a plurality of pairs of previously assigned reconstructed magnetic resonance combination images with an associated magnetic resonance spin species; in said computer automatically analyzing parameters of the reconstructed combination images in said database and the respective magnetic resonance spin species assigned thereto in order to obtain an analysis result and, from said analysis result, automatically determining generalized relationships that designate said assignment; and making the determined relationships available from the computer in electronic form for subsequent use during assignment of a magnetic resonance spin species to a reconstructed magnetic resonance combination image, which is not included in said database. ### Claim 6 (depends on 5) A method as claimed in claim 5 wherein said parameters are selected from the group consisting of parameters designating information about an examination object represented in the respective reconstructed combination images in the database, parameters in data acquisition techniques used for acquiring the data that is reconstructed in the reconstructed combination images of the database, parameters designating a sequence type of a data acquisition sequence used for acquiring the magnetic resonance data reconstructed in the reconstructed combination images of the database, parameters designating information read directly from the reconstructed combination images of the database, parameters representing local information derived from the reconstructed combination images of the database, and parameters representing global information derived from the reconstructed combination images of the database. ### Claim 7 (depends on 5) A method as claimed in claim 5 comprising determining said relationships in said computer using a machine learning algorithm. ### Claim 8 A magnetic resonance apparatus comprising: a computer loaded with predetermined relationships, determined from existing databases, into a computer that define assignment of magnetic resonance spin species to magnetic resonance combination images; a magnetic resonance data acquisition scanner configured to execute a multi-contrast magnetic resonance data acquisition measurement in which at least two echo times are produced, and to acquire at least two magnetic resonance datasets respectively during said at least two echo times; said computer being provided with said magnetic resonance datasets, and said computer being configured to reconstruct at least one combination image from said at least two magnetic resonance datasets; said computer being configured to use the loaded relationships to assign spin species represented in said determined at least one combination image to respective magnetic resonance spin species; and said computer being configured to make an electronic signal representing the assignment of the respective magnetic resonance spin species available from the computer in electronic form. ### Claim 9 A computer comprising: a memory; an input interface in communication with said memory, via which stored designations of a plurality of pairs of previously assigned reconstructed magnetic resonance combination images with an associated magnetic resonance spin species are loaded into the memory; a processor configured to automatically analyze parameters of the reconstructed combination images in said memory and the respective magnetic resonance spin species assigned thereto in order to obtain an analysis result and, from said analysis result, automatically determine generalized relationships that designate said assignment; an output interface; and said processor being configured to make the determined relationships available from the processor in electronic form via said output interface for subsequent use during assignment of a magnetic resonance spin species to a reconstructed magnetic resonance combination image, which is not included in said memory. ### Claim 10 A non-transitory, computer-readable data storage medium encoded with programming instructions, said storage medium being loaded into a control and evaluation computer of a magnetic resonance apparatus that comprises a magnetic resonance data acquisition scanner, and said programming instructions causing said control and evaluation computer to: receive predetermined relationships, determined from existing databases that define assignment of magnetic resonance spin species to magnetic resonance combination images; operate a magnetic resonance data acquisition scanner to execute a multi-contrast magnetic resonance data acquisition measurement in which at least two echo times are produced, and acquiring at least two magnetic resonance datasets respectively during said at least two echo times; reconstruct at least one combination image from said at least two magnetic resonance datasets; use the loaded relationships to assign spin species represented in said determined at least one combination image to respective magnetic resonance spin species; and make an electronic signal representing the assignment of the respective magnetic resonance spin species available from the control and evaluation computer in electronic form. ### Claim 11 A non-transitory, computer-readable data storage medium encoded with programming instructions, said storage medium being loaded into a control and evaluation computer of a magnetic resonance apparatus that comprises a magnetic resonance data acquisition scanner, and said programming instructions causing said control and evaluation computer to: receive a database that comprises stored designations of a plurality of pairs of previously assigned reconstructed magnetic resonance combination images with an associated magnetic resonance spin species; automatically analyze parameters of the reconstructed combination images in said database and the respective magnetic resonance spin species assigned thereto in order to obtain an analysis result and, from said analysis result, automatically determining generalized relationships that designate said assignment; and make the determined relationships available from the control and evaluation computer in electronic form for subsequent use during assignment of a magnetic resonance spin species to a reconstructed magnetic resonance combination image, which is not included in said database.