# US 10,310,032 B2 · Fluid channelling system of an NMR system and method of operating a system of this kind

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- Number: US 10,310,032 B2
- Document ID: US10310032B2
- Status: Granted
- Kind: B2
- Application number: 15/403,703
- Filed: 2017-01-11
- Published: 2017-07-13
- Granted: 2019-06-04
- Earliest claimed: 2016-01-12
- Assignees: Commissariat A L'energie Atomique Et Aux Energies Alternatives
- Applicants: Commissariat A L'energie Atomique Et Aux Energies Alternatives
- Inventors: Eric Bouleau; Daniel Lee
- Web page: https://patentgrep.com/patent/US10310032B2

## CPC

- G01R 33/31: Temperature control thereof
- F25B 9/00: Compression machines, plants or systems, in which the refrigerant is air or other gas of low boiling point
- F25B 9/10: with several cooling stages
- G01R 33/307: {specially adapted for moving the sample relative to the MR system, e.g. spinning mechanisms, flow cells or means for positioning the sample inside a spectrometer}
- G01R: MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES (indicating correct tuning of resonant circuits H03J3/12)
- F25B: REFRIGERATION MACHINES, PLANTS OR SYSTEMS; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS

## Abstract

Fluid channeling system (150) for NMR system (100), characterized in that the channeling system (150) includes an exhaust circuit (160) of the NMR system (100) comprising a first fluid circulation branch (161) and a second fluid circulation branch (162).

## Claims

### Claim 1

Fluid channelling system for NMR system, wherein the fluid channelling system includes:
an exhaust circuit of the NMR system configured to conduct a coolant fluid from a NMR device to a compressor of the NMR system, the exhaust circuit comprising:
a first branch which is a first fluid circulation branch, and
a second branch which is a second fluid circulation branch,
a feed circuit of the NMR system configured to conduct the coolant fluid from the compressor to the NMR device, the feed circuit comprising:
a third branch which is a third fluid circulation branch, and
a fourth branch which is a fourth fluid circulation branch, and
a first heat exchanger comprising at least one stage, wherein the first branch includes a pipe of the stage of the first heat exchanger and the third branch includes a pipe of the stage of the first heat exchanger, whereas the second and fourth branches do not include a pipe of the stage of the first heat exchanger, so that the fluid channelling system is configured to exchange heat between a fluid in the first branch and a fluid in the third branch in the stage of the first heat exchanger.

### Claim 2 (depends on 1)

The fluid channelling system according to claim 1, wherein the fluid channelling system comprises a first cryorefrigerator comprising at least one stage, wherein the second branch includes a pipe of the stage of the first cryorefrigerator upstream of the stage of the heat exchanger, so that the fluid channelling system is configured to cool the fluid in the fourth branch at a lower temperature than a fluid in the third branch.

### Claim 3 (depends on 1)

The fluid channelling system according to claim 1, wherein the fluid channelling system comprises at least one selected from the group consisting of a second heat exchanger and a second stage of the first heat exchanger, wherein the second branch includes a pipe of the second exchanger or second stage of the heat exchanger and the fourth branch includes a pipe of the second exchanger or second stage of the first heat exchanger, so that the fluid channelling system is configured to exchange heat between the fluid in the second branch and the fluid in the fourth branch in the second heat exchanger or second stage of the first heat exchanger.

### Claim 4 (depends on 1)

The fluid channelling system according to claim 1, wherein the third fluid circulation branch includes a plurality of sub-branches.

### Claim 5 (depends on 2)

The fluid channelling system according to claim 2, wherein the fluid channelling system comprises a second cryorefrigerator comprising at least one stage, a third cryorefrigerator comprising at least one stage, and a fourth cryorefrigerator comprising at least one stage, whereinthe third branch includes at least one pipe of the stage of the second cryorefrigerator, and the fourth branch includes a pipe of the stage of the third cryorefrigerator and a pipe of the stage of the fourth cryorefrigerator.

### Claim 6 (depends on 5)

The fluid channelling system according to claim 5, wherein the second cryorefrigerator and the third cryorefrigerator are the same cryorefrigerator.

### Claim 7 (depends on 5)

The fluid channelling system according to claim 5, wherein the first cryorefrigerator and the fourth cryorefrigerator are the same cryorefrigerator.

### Claim 8 (depends on 5)

The fluid channelling system according to claim 5, wherein the fluid channelling system includes a single cryorefrigerator.

### Claim 9 (depends on 3)

The fluid channelling system according to claim 3, wherein the fluid channelling system comprises at least one selected from the group consisting of a third heat exchanger and a third stage of the heat exchanger, wherein the second branch includes at least one pipe of the third heat exchanger or third stage of the heat exchanger, and wherein the fourth branch includes at least one pipe of the third exchanger or third stage of the heat exchanger.

### Claim 10 (depends on 1)

The fluid channelling system according to claim 1, wherein the second branch includes a flow rate regulator.

### Claim 11 (depends on 1)

The fluid channelling system according to claim 1, wherein at least one selected from the group consisting of (i) the third branch includes at least one flow rate regulator, and (ii) the fourth branch includes a flow rate regulator.

### Claim 12 (depends on 1)

NMR system including the fluid channelling system according to claim 1 and an NMR device.

### Claim 13 (depends on 1)

Method of operating the fluid channelling system according to claim 1, comprising conducting a coolant fluid simultaneously in the first and second branches.

### Claim 14 (depends on 1)

Method of operating the fluid channelling system according to claim 1, comprising at least one regulating action selected from the group consisting of:
(i) regulating fluid flow rates so that the fluid flow rates in the first and third branches are equal or substantially equal, and
(ii) regulating fluid flow rates so that the fluid flow rates in the second and fourth branches are equal or substantially equal.

### Claim 15 (depends on 4)

The fluid channelling system according to claim 4, wherein the plurality of sub-branches of the third branch includes at least one selected from the group consisting of (i) a first sub-branch configured for circulation of a first flow the function of which is to rotate a sample-holder by acting on blades or fins of a drive turbine of a rotor of a NMR device, the rotor including the sample-holder, (ii) a second sub-branch configured for circulation of a third flow the function of which is to create a bearing supporting the rotor in a stator of a NMR device, and (iii) a third sub-branch configured for circulation of a fourth flow the function of which is to cool a heat shield protecting a NMR device from thermal radiation.

### Claim 16 (depends on 6)

The fluid channelling system according to claim 6, wherein the stage of the second cryorefrigerator and the stage of the third cryorefrigerator are the same stage of the same cryorefrigerator.

### Claim 17 (depends on 7)

The fluid channelling system according to claim 7, wherein the stage of the first cryorefrigerator and the stage of the fourth cryorefrigerator are the same stage of the same cryorefrigerator.

### Claim 18 (depends on 8)

The fluid channelling system according to claim 8, wherein the single cryorefrigerator includes a first stage and a second stage, wherein the second and third cryorefrigerators are the first stage and the first and fourth cryorefrigerators are the second stage.

### Claim 19 (depends on 12)

Method of operating the NMR system according to claim 12, wherein the first and second branches conduct simultaneously the coolant fluid between a NMR device of the NMR system and a compressor of the NMR system.

### Claim 20

Fluid channelling system for NMR system, wherein the channelling system includes:
an exhaust circuit of the NMR system configured to conduct a coolant fluid from a NMR device to a compressor of the NMR system, the exhaust circuit comprising:
a first branch which is a first fluid circulation branch, and
a second branch which is a second fluid circulation branch,
a feed circuit of the NMR system configured to conduct the coolant fluid from the compressor to the NMR device, the feed circuit comprising:
a third branch which is a third fluid circulation branch, and
a fourth branch which is a fourth fluid circulation branch, and
wherein the fourth branch comprises a pipe of a cryorefrigerator, whereas the third branch does not comprise a pipe of the cryorefrigerator.

### Claim 21 (depends on 1)

The fluid channeling system according to claim 1, comprising a second heat exchanger comprising at least one stage, wherein the second branch includes a pipe of the stage of the second heat exchanger and the fourth branch includes a pipe of the stage of the second heat exchanger, so that the fluid channelling system is configured to exchange heat between a fluid in the second branch and a fluid in the fourth branch in the stage of the second heat exchanger.

### Claim 22 (depends on 21)

The fluid channeling system according to claim 21, wherein the first and third branches do not include a pipe of the stage of the second heat exchanger.
