# US 10,309,925 B2 · FET biosensor

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- Number: US 10,309,925 B2
- Document ID: US10309925B2
- Status: Granted
- Kind: B2
- Application number: 15/143,262
- Filed: 2016-04-29
- Published: 2016-11-03
- Granted: 2019-06-04
- Earliest claimed: 2015-04-30
- Assignees: Imec Vzw
- Applicants: Imec Vzw
- Inventors: Nadine Collaert; Voon Yew Thean
- Web page: https://patentgrep.com/patent/US10309925B2

## CPC

- G01N 27/4145: {specially adapted for biomolecules, e.g. gate electrode with immobilised receptors}
- G01N 27/414: Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS
- H10D 64/015: {removing at least parts of gate spacers, e.g. disposable spacers}
- H10D 64/512: {Disposition of the gate electrodes, e.g. buried gates}
- H10P 30/222: {characterised by the angle between the ion beam and the crystal planes or the main crystal surface (characterised by the angle between the ion beam and the mask H10P30/221)}
- G01N: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES (measuring or testing apparatus or processes other than immunoassay, involving enzymes or microorganisms C12M, C12Q)
- H10D: INORGANIC ELECTRIC SEMICONDUCTOR DEVICES
- H10P: GENERIC PROCESSES OR APPARATUS FOR THE MANUFACTURE OR TREATMENT OF DEVICES COVERED BY CLASS H10

## Abstract

The disclosed technology relates generally to semiconductor devices, and more particularly to semiconductor devices such as field-effect transistor devices configured for biomolecule sensing. In one aspect, a semiconductor chip comprises at least one field-effect transistor device which comprises a source, a drain, a gate stack and a channel region formed between the source and the drain. The gate stack only partially overlaps the channel region at the source side and/or at the drain side, such that a non-overlapped channel region at the source side and/or at the drain side is formed, where the non-overlapped channel region is configured for sensing biomolecules.

## Claims

### Claim 1

A method of fabricating a semiconductor chip configured for bio-sensing, the method comprising:
obtaining a substrate comprising at least one semiconductor layer;
providing a gate stack on the substrate;
providing a doped drain region in and/or on the substrate; and
providing a doped source region in and/or on the substrate,
wherein the doped drain region and/or the doped source region have an underlap region laterally between the gate stack and the source region and/or between the gate stack and the drain region, such that the underlap region is configured for sensing biomolecules attached thereto.

### Claim 2 (depends on 1)

The method according to claim 1, wherein providing the doped source region and/or providing the doped drain region includes performing a tilted ion implantation.

### Claim 3 (depends on 1)

The method according to claim 1, further comprising, prior to providing the doped source region and/or providing the doped drain region, providing a spacer adjacent the gate stack at a side oriented towards the source region and/or a spacer adjacent the gate stack at a side oriented towards the drain region.

### Claim 4 (depends on 3)

The method according to claim 3, wherein providing the doped source region and/or providing the doped drain region comprises growing an in-situ doped semiconductor layer.

### Claim 5 (depends on 3)

The method according to claim 3, wherein providing the doped source region and/or providing the doped drain region comprises depositing a doped spin-on glass and outdiffusing dopants from the doped spin-on glass into the source region and/or the drain region.

### Claim 6 (depends on 3)

The method according to claim 3, further comprising, after providing the doped source region and/or providing the doped drain region, removing the spacer at the side of the gate stack oriented towards the source region and/or removing the spacer at the side of the gate stack oriented towards the drain region.

### Claim 7 (depends on 1)

The method according to claim 1, further comprising back end-of-the-line (BEOL) processing of the semiconductor chip.

### Claim 8 (depends on 1)

The method according to claim 1, wherein providing the doped drain region includes covering a source side of the substrate such that the source side is not doped or further doped with a source dopant.

### Claim 9

A semiconductor chip configured for bio-sensing, the semiconductor chip comprising:
at least one field-effect transistor (FET) device comprising a source, a drain, a gate stack and a channel region formed between the source and the drain,
wherein the gate stack partially overlaps the channel region at a source side and/or at a drain side, such that a non-overlapped channel region is formed at the source side and/or at the drain side that is configured for sensing biomolecules.

### Claim 10 (depends on 9)

The semiconductor chip according to claim 9, further comprising a spacer formed on the substrate between the gate stack and the drain.

### Claim 11 (depends on 9)

The semiconductor chip according to claim 9, wherein the gate stack overlaps the drain.

### Claim 12 (depends on 9)

The semiconductor chip according to claim 9, further comprising a reference FET having a gate stack which completely overlaps the channel.

### Claim 13 (depends on 9)

The semiconductor chip according to claim 9, wherein the at least one FET comprises a backgate.

### Claim 14 (depends on 9)

The semiconductor chip according to claim 9, wherein the channel region has an increased body factor.

### Claim 15 (depends on 9)

The semiconductor chip according to claim 9, wherein the non-overlapped channel region comprises a semiconductor surface having formed thereon molecules having functional groups configured to bind to the biomolecules.

### Claim 16 (depends on 9)

The semiconductor chip according to claim 9, wherein the channel region is undoped.

### Claim 17 (depends on 9)

A method of using the semiconductor chip according to claim 9 for biomolecule sensing.

### Claim 18 (depends on 17)

The method of claim 17, wherein the semiconductor chip comprises a backgate, and wherein a sub-threshold sweep is adjusted by adjusting a voltage on the backgate.
