# US 10,307,613 B2 · Internal body cavity therapeutic applicator arrangements and methods for using the same > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,307,613 B2 - Document ID: US10307613B2 - Status: Granted - Kind: B2 - Application number: 15/425,365 - Filed: 2017-02-06 - Published: 2017-05-25 - Granted: 2019-06-04 - Earliest claimed: 2011-09-30 - Assignees: Memorial Sloan Kettering Cancer Center; Gc Medtech LLC - Applicants: Memorial Sloan-Kettering Cancer Center; Gc Medtech LLC - Inventors: Gary A. Lamoureux; Gil'Ad N. Cohen; Karyn Goodman - Web page: https://patentgrep.com/patent/US10307613B2 ## CPC - A61N 5/1002: {Intraluminal radiation therapy} - A61B 1/018: for receiving instruments - A61B 34/20: Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis - A61B 90/10: for stereotaxic surgery, e.g. frame-based stereotaxis - A61B 90/39: {Markers, e.g. radio-opaque or breast lesions markers} - A61M 25/0026: {Multi-lumen catheters with stationary elements (catheter assemblies comprising a catheter in combination with a guide tube, sheath or sleeve A61M2025/0681; catheters comprising telescoping coaxial elements A61M2025/0175)} - A61M 25/003: {characterized by features relating to least one lumen located at the distal part of the catheter, e.g. filters, plugs or valves (catheter tips A61M25/0067)} - A61M 25/0067: {characterised by the distal end, e.g. tips (A61M25/0054, A61M25/04 take precedence; balloon catheters A61M25/10)} - A61M 25/0105: {Steering means as part of the catheter or advancing means; Markers for positioning (systems for detection of markers A61B)} - A61M 25/09: Guide wires - A61M 25/1011: {Multiple balloon catheters} - A61N 5/1007: {Arrangements or means for the introduction of sources into the body} - A61N 5/1014: {Intracavitary radiation therapy} - A61B 2090/101: {for stereotaxic radiosurgery} - A61M 2025/0008: {having visible markings on its surface, i.e. visible to the naked eye, for any purpose, e.g. insertion depth markers, rotational markers or identification of type} - A61M 2025/004: {characterized by lumina being arranged circumferentially} - A61M 2025/1013: {with concentrically mounted balloons, e.g. being independently inflatable} - A61M 2025/1093: {having particular tip characteristics} - A61N 2005/1003: {having means for centering a radioactive source within the lumen, e.g. balloons} - A61N 2005/1018: {with multiple channels for guiding radioactive sources} - A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B) - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} ## Abstract An apparatus for providing at least one treatment to at least one tissue having a first structural arrangement configured to expand a first portion at a distal end of the apparatus, a second structural arrangement configured to expand a second portion at the distal end and at least one lumen associated with at least one of the first structural arrangement and/or the second structural arrangement. The first structural arrangement and/or the second structural arrangement can be configured to position the at least one lumen at a particular position with respect to the tissue. A tip is configured to aid in the insertion of the apparatus into the tissue(s). ## Claims ### Claim 1 An apparatus for providing at least one treatment to at least one tissue, comprising: a first inflation structure configured to expand a first portion at a distal end of the apparatus; a second inflation structure configured to expand a second portion at the distal end; and at least one lumen extending from a proximal end of the apparatus to the distal end, and having an opening at the proximal end, wherein the at least one lumen is located between and separate from the first inflation structure and the second inflation structure; wherein the first inflation structure is configured to position the at least one lumen at a particular position with respect to the at least one tissue based on an expansion of the first portion, and wherein the second inflation structure is configured to position the at least one lumen at the particular position with respect to the at least one tissue based on an expansion of the second portion, and wherein at least one of the first inflation structure or the second inflation structure is a baffle filled with at least one of sterile water or air. ### Claim 2 (depends on 1) The apparatus of claim 1, further comprising a tip portion provided at the distal end and configured to facilitate an insertion of the apparatus into the at least one tissue. ### Claim 3 (depends on 1) The apparatus of claim 1, wherein the second inflation structure is configured to expand the at least one tissue. ### Claim 4 (depends on 1) The apparatus of claim 1, wherein the at least one lumen is configured and structured to provide a radiation source through the opening. ### Claim 5 (depends on 1) The apparatus of claim 1, wherein the at least one lumen comprises at least eight lumens equally spaced apart circumferentially around the distal end. ### Claim 6 (depends on 5) The apparatus of claim 5, wherein one of the lumens is visibly labeled or marked to provide a reference point for all of the lumens. ### Claim 7 (depends on 1) The apparatus of claim 1, wherein the at least one lumen is configured to receive a treatment option. ### Claim 8 (depends on 7) The apparatus of claim 7, wherein the treatment option is at least one of a radiation source or a pharmacological agent. ### Claim 9 (depends on 1) The apparatus of claim 1, further comprising a second lumen located substantially in a center of the apparatus. ### Claim 10 (depends on 1) The apparatus of claim 1, wherein the apparatus is configured to be guided into a tubular structure using at least one of at least an endoscope, a cable or a wire. ### Claim 11 (depends on 1) The apparatus of claim 1, further comprising markers at least one of spaced equally apart at the proximal end of the apparatus to determine a distance at which the apparatus is inserted into the at least one tissue or spaced along the distal end which are provided to be detected by an imaging device to aid in insertion of the apparatus. ### Claim 12 (depends on 1) The apparatus of claim 1, wherein the first inflation structure and the second inflation structure are baffles filled with at least one of the sterile water or the air, and further comprising at least one of a single baffle source for inflating the first inflation structure and the second inflation structure or two baffle sources, one of the baffle sources provided for inflating the first inflation structure and the other of the baffle sources provided for inflating the second inflation structure. ### Claim 13 (depends on 1) The apparatus of claim 1, further comprising at least one of a single source for inflating the first inflation structure and the second inflation structure or two sources, one of the sources provided for inflating the first inflation structure and the other of the sources provided for inflating the second inflation structure. ### Claim 14 (depends on 1) The apparatus of claim 1, wherein the apparatus includes at least one of an anorectal applicator, an esophageal applicator, a sigmoid applicator or a colon applicator. ### Claim 15 A method for treating a patient using an apparatus configured to provide at least one radiation treatment to at least one tissue of the patient, comprising: inserting the apparatus into the at least one tissue; expanding a first portion at a distal end of the apparatus using a first inflation structure; expanding a second portion at the distal end using a second inflation structure; positioning at least one lumen at a particular position with respect to the at least one tissue, wherein at least one lumen extends from a proximal end of the apparatus to the distal end, and has an opening at the proximal end, and wherein the at least one lumen is located between and separate from the first inflation structure and the second inflation structure; inserting at least one radiation source into the at least one lumen; applying, using the at least one radiation source, the at least one radiation treatment directly to an internal portion of the at least one tissue which includes a disorder; contracting at least one of the first inflation structure or the second inflation structure; and removing the radiation source and the apparatus from the at least one tissue; wherein at least one of the first inflation structure or the second inflation structure is a baffle. ### Claim 16 (depends on 15) The method of claim 15, further comprising using an imaging device to aid in an insertion of the apparatus. ### Claim 17 (depends on 16) The method of claim 16, further comprising providing markers at least one of spaced along the distal end capable of being detected by the imaging device to aid in the insertion of the apparatus or spaced equally apart at the proximal end of the apparatus to determine a distance of an insertion of the apparatus into the at least one tissue. ### Claim 18 (depends on 17) The method of claim 17, further comprising marking a further distance marker on the apparatus, and reinserting the apparatus only to a position of the further marked distance marker. ### Claim 19 (depends on 15) The method of claim 15, wherein the baffle is filled with at least one of sterile water or air. ### Claim 20 (depends on 15) The method of claim 15, wherein both of the first inflation structure and the second inflation structure are baffles filled with at least one of sterile water or air.