# US 10,307,446 B2 · Cannabis extraction method and compositions

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- Number: US 10,307,446 B2
- Document ID: US10307446B2
- Status: Granted
- Kind: B2
- Application number: 15/037,817
- Filed: 2015-03-10
- Published: 2016-10-06
- Granted: 2019-06-04
- Earliest claimed: 2014-03-21
- Assignees: St&T International, Inc.
- Applicants: ST&T International, Inc.
- Inventors: Michael Scott
- Web page: https://patentgrep.com/patent/US10307446B2

## CPC

- A61K 36/3482: {Cannabis}
- A61K 9/0014: {Skin, i.e. galenical aspects of topical compositions (non-active ingredients are additionally classified in A61K47/00; A61K9/0009, A61K9/0021, A61K9/7015, A61K9/7023 take precedence; cosmetic preparations A61K8/00, A61Q; preparations for wound dressings or bandages A61L26/00)}
- A61K 36/886: Aloeaceae (Aloe family), e.g. aloe vera
- A61P 17/00: Drugs for dermatological disorders
- A61P 17/02: for treating wounds, ulcers, burns, scars, keloids, or the like
- A61P 17/06: Antipsoriatics
- A61P 17/10: Anti-acne agents
- A61P 17/12: Keratolytics, e.g. wart or anti-corn preparations
- A61P 17/16: Emollients or protectives, e.g. against radiation
- A61P 35/00: Antineoplastic agents
- A61K 2236/00: Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

## Abstract

The present invention provides methods of extracting Cannabis plant material through use of aloe, compositions comprising the resulting Cannabis aloe extracts, methods of using the extracts to ameliorate skin conditions, and applicators for applying the extracts topically.

## Claims

### Claim 1

A method of making a freeze dried solid form of a Cannabis/Aloe vera extract consisting essentially of:
a) obtaining cannabis selected from the group consisting of Cannabis sativa, Cannabis indica, Cannabis ruderalis and combinations thereof wherein the cannabis has been processed by one or more of cutting into pieces, milling, drying or powdering to thereby yield processed Cannabis;
b) mixing the processed Cannabis with an extractant consisting essentially of an Aloe vera leaf liquid to form a cannabis/aloe vera mixture;
c) extracting the Cannabis/aloe vera mixture by heating from about 40° C. to about 100° C. for about 1 to about 10 hours, thereby resulting in a Cannabis/Aloe vera extract;
d) separating lipids and waxy ballast from the Cannabis/Aloe vera extract by filtration, centrifugation, screening, and/or decantation; and
e) converting the Cannabis/Aloe vera extract to a solid form by freeze drying, wherein the cannabis consists essentially of cannabinoids.

### Claim 2 (depends on 1)

The method of claim 1, wherein the Cannabis is Cannabis sativa.

### Claim 3 (depends on 1)

The method of claim 1, wherein about one part to about 50 parts by weight of the Cannabis is mixed with about one part to about 100 parts by weight of the Aloe vera leaf liquid.

### Claim 4 (depends on 1)

The method of claim 1, wherein the extraction mixture further consists essentially of at least one additional extractant selected from the group consisting of alcohols, ketones, and esters.

### Claim 5 (depends on 4)

The method of claim 4, wherein the additional extractant is selected from the group consisting of methanol, ethanol, propanol, n-propanol, iso-propanol, n-butanol, tert-butanol, acetone, methyl ethyl ketone, methoxyethanol, 2-butoxyethanol, diethyl ether, acetone, butanone, ethyl acetate, and mixtures thereof.

### Claim 6 (depends on 1)

The method of claim 1, wherein the cannabinoids are cannabadiol and Δ9-tetrahydrocannabinol.

### Claim 7 (depends on 1)

The method of claim 1, wherein the weight ratio of the Aloe vera leaf liquid to the Cannabis is about 1:1 to about 100:1.

### Claim 8 (depends on 1)

The method of claim 1, wherein the weight ratio of the Aloe vera leaf liquid to the Cannabis is about 5:1 to about 20:1.

### Claim 9 (depends on 1)

The method of claim 1, wherein the Cannabis is Cannabis indica.

### Claim 10 (depends on 1)

The method of claim 1, wherein the Cannabis is Cannabis ruderalis.