# US 10,307,420 B2 · Treating sexual desire disorders with flibanserin

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- Number: US 10,307,420 B2
- Document ID: US10307420B2
- Status: Granted
- Kind: B2
- Application number: 16/125,883
- Filed: 2018-09-10
- Published: 2019-01-03
- Granted: 2019-06-04
- Earliest claimed: 2001-10-20
- Assignees: Sprout Pharmaceuticals, Inc.
- Applicants: Sprout Pharmaceuticals, Inc.
- Inventors: Franco Borsini; Kenneth Robert Evans
- Web page: https://patentgrep.com/patent/US10307420B2

## CPC

- A61K 31/496: Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
- A61P 15/00: Drugs for genital or sexual disorders (for disorders of sex hormones A61P5/24); Contraceptives
- A61P 15/10: for impotence
- A61P 25/18: Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A61P 25/22: Anxiolytics
- A61P 25/24: Antidepressants
- A61P 43/00: Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

## Abstract

The invention relates to the use of flibanserin, or a pharmaceutically acceptable acid addition salt thereof, for the treatment of disorders of sexual desire.

## Claims

### Claim 1

A method of treating decreased sexual desire in an adult human patient, comprising orally administering one or more capsule or tablet comprising a therapeutically effective amount of flibanserin or a pharmaceutically acceptable acid addition salt thereof, and at least one excipient, to the patient to treat decreased sexual desire.

### Claim 2 (depends on 1)

The method according to claim 1, wherein the patient is female.

### Claim 3 (depends on 1)

The method according to claim 1, wherein the patient is male.

### Claim 4 (depends on 1)

The method according to claim 1, wherein the amount administered is between about 0.1 mg and 400 mg per day of flibanserin or a pharmaceutically acceptable acid addition salt thereof.

### Claim 5 (depends on 1)

The method according to claim 1, wherein the amount administered is between about 1 mg and 300 mg per day of flibanserin or a pharmaceutically acceptable acid addition salt thereof.

### Claim 6 (depends on 1)

The method according to claim 1, wherein the amount administered is in one capsule or tablet containing between about 0.01 mg and 100 mg of flibanserin or a pharmaceutically acceptable acid addition salt thereof.

### Claim 7 (depends on 1)

The method according to claim 1, wherein the amount administered is in one capsule or tablet containing between about 0.1 mg and 50 mg of flibanserin or a pharmaceutically acceptable acid addition salt thereof.

### Claim 8

A method of treating absent sexual desire in an adult human patient, comprising orally administering one or more capsule or tablet comprising a therapeutically effective amount of flibanserin or a pharmaceutically acceptable acid addition salt thereof, and at least one excipient, to the patient to treat decreased sexual desire.

### Claim 9 (depends on 8)

The method according to claim 8, wherein the patient is female.

### Claim 10 (depends on 8)

The method according to claim 8, wherein the patient is male.

### Claim 11 (depends on 8)

The method according to claim 8, wherein the amount administered is between about 2 mg and 200 mg per day of flibanserin or a pharmaceutically acceptable acid addition salt thereof.

### Claim 12 (depends on 8)

The method according to claim 8, wherein the amount administered is between about 0.1 mg and 100 mg per day of flibanserin or a pharmaceutically acceptable acid addition salt thereof.

### Claim 13 (depends on 8)

The method according to claim 8, wherein the amount administered is in one capsule or tablet containing about 150 mg of flibanserin or a pharmaceutically acceptable acid addition salt thereof.

### Claim 14

A method of treating inhibited sexual desire in an adult human patient, comprising orally administering one or more capsule or tablet comprising a therapeutically effective amount of flibanserin or a pharmaceutically acceptable acid addition salt thereof, and at least one excipient, to the patient to treat decreased sexual desire.

### Claim 15 (depends on 14)

The method according to claim 14, wherein the patient is female.

### Claim 16 (depends on 14)

The method according to claim 14, wherein the patient is male.

### Claim 17 (depends on 14)

The method according to claim 14, wherein the amount administered is between about 0.1 mg and 400 mg per day of flibanserin or a pharmaceutically acceptable acid addition salt thereof.

### Claim 18 (depends on 14)

The method according to claim 14, wherein the amount administered is in one capsule or tablet containing about 100 mg of flibanserin or a pharmaceutically acceptable acid addition salt thereof.

### Claim 19 (depends on 14)

The method according to claim 14, wherein the amount administered is in one capsule or tablet containing about 80 mg of flibanserin or a pharmaceutically acceptable acid addition salt thereof.

### Claim 20 (depends on 14)

The method according to claim 14, wherein the amount administered is in one capsule or tablet containing about 50 mg of flibanserin or a pharmaceutically acceptable acid addition salt thereof.
