# US 10,307,253 B2 · System for improving cardiac function by sealing a partitioning membrane within a ventricle

> Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt

- Number: US 10,307,253 B2
- Document ID: US10307253B2
- Status: Granted
- Kind: B2
- Application number: 13/773,235
- Filed: 2013-02-21
- Published: 2013-06-27
- Granted: 2019-06-04
- Earliest claimed: 1999-08-09
- Assignees: Edwards Lifesciences Corporation
- Applicants: Edwards Lifesciences Corporation
- Inventors: Alexander Khairkhahan; Serjan D. Nikolic; Hugh R. Sharkey
- Web page: https://patentgrep.com/patent/US10307253B2

## CPC

- A61F 2/2487: {Devices within the heart chamber, e.g. splints}
- A61B 17/0057: {Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect (sutures A61B17/04; closing rectum or urethra near body surface A61F2/0009)}
- A61B 17/12022: {Occluding by internal devices, e.g. balloons or releasable wires (plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20)}
- A61B 17/12122: {within the heart (for closing a cardiac septal defect A61B17/0057)}
- A61B 17/12172: {having a pre-set deployed three-dimensional shape (methods of manufacturing A61B2017/00526)}
- A61B 17/12195: {comprising a curable material}
- A61B 17/1214: {Coils or wires}
- A61B 2017/00243: {cardiac}
- A61B 2017/00557: {inflatable (A61B2017/22051 takes precedence)}
- A61B 2017/00575: {for closure at remote site, e.g. closing atrial septum defects}
- A61B 2017/00579: {Barbed implements}
- A61B 2017/00592: {Elastic or resilient implements}
- A61B 2017/00597: {Implements comprising a membrane}
- A61B 2017/00601: {Implements entirely comprised between the two sides of the opening}
- A61B 2017/00615: {Implements with an occluder on one side of the opening and holding means therefor on the other}
- A61B 2017/00632: {Occluding a cavity, i.e. closing a blind opening}
- A61B 2017/00867: {shape memory effect}
- A61B 2017/0649: {Coils or spirals}
- A61B 2017/12095: {Threaded connection}
- A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C)
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)

## Abstract

Partitioning devices that may be secured and sealed within a heart chamber for separating a patient's heart chamber into a productive portion and a non-productive portion are described herein. The partitioning devices described herein may include a reinforced membrane with outwardly biased members. The reinforced membrane may have a central hub with a distally extending support stem with a plurality of feet which extend radially from a centerline axis and preferably have ends that are aligned in a common plane. These devices may be secured within the heart chamber by sealing them to the wall of the heart chamber, for example, by inflating an inflatable element on the periphery of the device. The non-productive portion may be filled with a material, including occlusive materials. Sealing and/or filling the non-productive portion formed by the devices described herein may help prevent leakage from the non-productive region.

## Claims

### Claim 1

A device for partitioning a ventricle of a patient's heart into a productive portion and a non-productive portion, the device comprising:
a membrane and a membrane support frame, the membrane and the membrane support frame sized to span the patient's ventricle, wherein the membrane and the membrane support frame are configured to have a collapsed configuration and an expanded configuration, wherein the membrane and membrane support frame are concave to form a trumpet-shaped surface in the expanded configuration;
at least one securing element on a peripheral portion of the membrane or membrane support frame configured to secure the membrane to a wall of the ventricle; and
a container secured to the device and positioned between the membrane support frame and the non-productive portion of the subject's ventricle when the device is deployed in the subject's ventricle.

### Claim 2 (depends on 1)

The device of claim 1, wherein the container is secured to the membrane.

### Claim 3 (depends on 1)

The device of claim 1, wherein the container extends from a peripheral portion of the membrane.

### Claim 4 (depends on 1)

The device of claim 1, wherein the container is configured to substantially conform to the ventricular wall.

### Claim 5 (depends on 1)

The device of claim 1, wherein the container is configured as a bag.

### Claim 6 (depends on 1)

The device of claim 1, wherein the container is expandable.

### Claim 7 (depends on 1)

The device of claim 1, wherein the container is made of a flexible material.

### Claim 8 (depends on 1)

The device of claim 1, wherein the container is configured to be filled with a fluid.

### Claim 9 (depends on 1)

The device of claim 1, wherein the container is configured to be filled with one or more coils.

### Claim 10 (depends on 1)

The device of claim 1, further comprising a valve providing access into the container.

### Claim 11 (depends on 10)

The device of claim 10, wherein the valve is a one-way valve configured to allow the container to passively fill with blood from the ventricle.

### Claim 12 (depends on 1)

The device of claim 1, further comprising a central hub.

### Claim 13 (depends on 1)

The device of claim 1, further comprising a stem.

### Claim 14 (depends on 13)

The device of claim 13, wherein the stem is positioned within the container.

### Claim 15 (depends on 1)

The device of claim 1, further comprising:
a central hub, the membrane support frame extending from a first side of the central hub; and
a foot extending form a second side of the central hub.

### Claim 16 (depends on 15)

The device of claim 15, wherein the foot is entirely encompassed by the container.

### Claim 17 (depends on 1)

The device of claim 1, wherein the membrane support frame is resilient.