# US 10,307,126 B2 · Computed tomography perfusion imaging

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- Number: US 10,307,126 B2
- Document ID: US10307126B2
- Status: Granted
- Kind: B2
- Application number: 14/852,386
- Filed: 2015-09-11
- Published: 2016-03-17
- Granted: 2019-06-04
- Earliest claimed: 2014-09-11
- Assignees: Shenyang Neusoft Medical Systems Co., Ltd.
- Applicants: Shenyang Neusoft Medical Systems Co., Ltd.
- Inventors: Yao Liu
- Web page: https://patentgrep.com/patent/US10307126B2

## CPC

- A61B 6/507: {for determination of haemodynamic parameters, e.g. perfusion CT}
- A61B 6/032: {Transmission computed tomography [CT]}
- A61B 6/461: {Displaying means of special interest}
- A61B 6/486: {involving generating temporal series of image data}
- A61B 6/5217: {extracting a diagnostic or physiological parameter from medical diagnostic data}
- A61B 6/5247: {combining images from an ionising-radiation diagnostic technique and a non-ionising radiation diagnostic technique, e.g. X-ray and ultrasound}
- G16H 50/30: for calculating health indices; for individual health risk assessment
- A61B 5/0263: {using NMR}
- G01R 33/56366: {Perfusion imaging}
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- G16H: HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G01R: MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES (indicating correct tuning of resonant circuits H03J3/12)

## Abstract

A method of computed tomography (CT) perfusion imaging includes: obtaining perfusion data by using a CT device to scan a present perfusion subject; performing calculations of the perfusion data by using two perfusion calculation methods to obtain perfusion parameters of each of said two perfusion calculation methods as initial perfusion parameters of each of said two perfusion calculation methods; performing calculations by using the initial perfusion parameters based on weights of said two perfusion calculation methods to obtain target perfusion parameters; and forming a target perfusion image of the present perfusion subject according to the target perfusion parameters.

## Claims

### Claim 1

A method of computed tomography (CT) perfusion imaging, comprising:
obtaining perfusion data by using a CT device to scan a present perfusion subject;
performing calculations of the perfusion data by using two perfusion calculation methods to obtain perfusion parameters of each of said two perfusion calculation methods as initial perfusion parameters of each of said two perfusion calculation methods;
performing calculations by using the initial perfusion parameters based on weights of said two perfusion calculation methods to obtain target perfusion parameters; and
forming a target perfusion image of the present perfusion subject according to the target perfusion parameters.

### Claim 2 (depends on 1)

The method of claim 1, wherein the perfusion data is a time density curve.

### Claim 3 (depends on 1)

The method according to claim 1, further comprising:
obtaining inputted configuration coefficients for said two perfusion calculation methods in response to input operations of the configuration coefficients;
performing re-calculations by using the initial perfusion parameters according to the inputted configuration coefficients for said two perfusion calculation methods to obtain new target perfusion parameters; and
forming the target perfusion image of the present perfusion subject according to the new target perfusion parameters.

### Claim 4 (depends on 1)

The method according to claim 1, further comprising:
identifying lesion areas in the target perfusion image according to the target perfusion parameters of pixels of the target perfusion image, and providing lesion information of the lesion areas.

### Claim 5 (depends on 1)

The method according to claim 1, further comprising:
searching the target perfusion parameters and the initial perfusion parameters according to a select region in response to a request operation of displaying the perfusion parameters of the select region in the target perfusion image, and
displaying the target perfusion parameters and the initial perfusion parameters corresponding to the select region.

### Claim 6 (depends on 1)

The method according to claim 1, further comprising:
forming perfusion images of the present perfusion subject as initial perfusion images by using the initial perfusion parameters of each of said two perfusion calculation methods; and
displaying the initial perfusion images and the target perfusion image.

### Claim 7

A device for forming a computed tomography (CT) perfusion image, comprising:
a storage medium to store machine readable instructions of a control logic for CT perfusion imaging; and
a processor which reads and executes the machine readable instructions to:
obtain perfusion data by using a CT device to scan a present perfusion subject;
perform calculations of the perfusion data by using two perfusion calculation methods to obtain perfusion parameters of each of said two perfusion calculation methods as initial perfusion parameters of each of said two perfusion calculation methods;
perform calculations by using the initial perfusion parameters based on weights of said two perfusion calculation methods to obtain target perfusion parameters; and
form a target perfusion image of the present perfusion subject according to the target perfusion parameters.

### Claim 8 (depends on 7)

The device according to claim 7, wherein the perfusion data is a time density curve.

### Claim 9 (depends on 7)

The device according to claim 7, wherein the machine readable instructions further cause the processor to:
obtain inputted configuration coefficients for said two perfusion calculation methods in response to input operations of the configuration coefficients;
perform re-calculations by using the initial perfusion parameters according to the inputted configuration coefficients for said two perfusion calculation methods to obtain new target perfusion parameters; and
form a target perfusion image of the present perfusion subject according to the new target perfusion parameters.

### Claim 10 (depends on 7)

The device according to claim 7, wherein the machine readable instructions further cause the processor to:
identify lesion areas in the target perfusion image according to the target perfusion parameters of pixels of the target perfusion image, and provide lesion information of the lesion areas.

### Claim 11 (depends on 7)

The device according to claim 7, wherein the machine readable instructions further cause the processor to:
search the target perfusion parameters and the initial perfusion parameters according to a select position in response to a request operation of displaying the perfusion parameters of the select region in the target perfusion image, and
display the target perfusion parameters and the initial perfusion parameters corresponding to the select region.

### Claim 12 (depends on 7)

The device according to claim 7, wherein the machine readable instructions further cause the processor to:
form perfusion images of the present perfusion subject as initial perfusion images by using the initial perfusion parameters of each of said two perfusion calculation methods; and
display the initial perfusion images and the target perfusion image.