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US 10,300,125 B2Granted
Immunogenic influenza composition
AssigneeBiological Mimetics, Inc.
InventorsPeter L Nara, Gregory J Tobin, George Lin
Life of this patent
Estimating the term…
Abstract
Novel compositions useful as influenza immunogens are provided. The compositions enable a host response to immunogen sites normally not recognized by a host.
Claims19
An isolated composition comprising:
- (a) a cross reactive epitope that stimulates an immune response to influenza virus;
- and
- (b) an immunodominant surface epitope, that is immunodampened, of influenza virus hemagglutinin,
- wherein
- (i) said dampened immunodominant surface epitope is not as immunodominant as said immunodominant surface epitope in a wild type influenza virus;
- and
- (ii) said cross reactive epitope is subdominant in a wild type influenza virus.
4 more elements
Dependencies are inferred from the claim text.