Methods for treating antipsychotic-induced weight gain
AssigneeAlkermes Pharma Ireland Limited
InventorsDaniel Deaver, Mark Todtenkopf
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Abstract
The present invention relates to the discovery of a novel opioid modulator effective in reducing pharmacologically induced weight gain associated with atypical antipsychotic use. The present invention provides methods of reducing antipsychotic induced weight gain, methods for suppressing food intake and reducing ghrelin levels induced by atypical antipsychotic medications in a patient.
Claims20
A composition comprising olanzapine and a compound of formula
- or a pharmaceutically acceptable salt thereof.
A method of treating a disease or disorder selected from schizophrenia, bipolar disorder, acute mania, bipolar I disorders with a single manic episode, or bipolar I disorders manifesting a mixed most recent episode comprising administering a composition comprising olanzapine and a compound of formula
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.