Method for treating a gastrointestinal disorder in a mammal using bacteroides thetaiotaomicron and compositions thereof
AssigneesMayo Foundation for Medical Education and Research, The Regents of the University of California
InventorsPurna C. Kashyap, Michael Fischbach
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Abstract
This document provides materials and methods related to bacterial compositions containing at least one bacterial organism having tryptophan decarboxylase activity. For example, bacterial compositions containing at least one bacterial organism having tryptophan decarboxylase activity and methods for using such bacterial compositions to improve gastrointestinal epithelial function and/or to treat gastrointestinal disorders are provided.
Claims15
A method for treating a gastrointestinal disorder in a mammal, said method comprising administering a composition comprising at least one live bacterial organism having exogenous tryptophan decarboxylase activity to said mammal under conditions wherein gastrointestinal function of said mammal is improved, wherein said at least one bacterial organism is Bacteroides thetaiotaomicron.
A composition comprising at least one bacterial organism comprising exogenous tryptophan decarboxylase activity, wherein said at least one bacterial organism is Bacteroides thetaiotaomicron.
A composition comprising tryptophan and at least one bacterial organism comprising exogenous tryptophan decarboxylase activity, wherein said at least one bacterial organism is Bacteroides thetaiotaomicron.
Dependencies are inferred from the claim text.