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US 10,300,031 B2Granted
Pharmaceutical compositions for treating chronic pain and pain associated with neuropathy
AssigneeTrinity Laboratories, Inc.
InventorChandra Ulagaraj Singh
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Abstract
The present invention provides methods and compositions for the treatment of neuropathic pain. In certain embodiments, compositions comprising an dextromethorphan (or other N-methyl-D-aspartate receptor antagonist), tramadol, and gabapentin can synergistically act to reduce pain in a human patient. Pharmaceutical compositions may also comprise a capsaicinoid, an esterified capsaicinoid, and/or a tricyclic antidepressant.
Claims8
A pharmaceutical composition comprising a synergistic combination of:
- a) 35 mg of tramadol or a pharmaceutically acceptable salt thereof;
- b) 35 mg of dextromethorphan or a pharmaceutically acceptable salt thereof;
- and
- c) 90 mg of gabapentin or a pharmaceutically acceptable salt thereof.
1 more element
Dependencies are inferred from the claim text.