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US 10,300,021 B2Granted
Intraorally rapidly disintegrating tablet
AssigneeTeijin Pharma Limited
InventorsTomoya Akutagawa, Masahiko Narasaki
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Abstract
The present invention provides an intraorally rapidly disintegrating tablet that can be formed using an ordinary apparatus, that has hardness with no practical problem and that disintegrates rapidly with good feeling in the oral cavity. The present invention is intraorally rapidly disintegrating tablet produced by compression molding of a granule coated with a disintegrant, in which the granule contains a disintegrant also inside thereof and a drug except ambroxol hydrochloride inside and/or outside thereof.
Claims10
An intraorally rapidly disintegrating tablet produced by compression of
- a granule, wherein the granule consists of a single coating layer and an inside, and contains no drug;
- and
- a drug except ambroxol hydrochloride,
- wherein the inside of the granule comprises a disintegrant, and is prepared from a powder comprising the disintegrant, and then the granule is coated with the single coating layer consisting of the disintegrant;
- and
- wherein preparation of the granule comprises a step of swelling the disintegrant with water and/or ethanol prior to the preparation thereof and a step of drying the granule after coating with the disintegrant.
3 more elements
Dependencies are inferred from the claim text.