Nasolacrimal drainage system implants for drug therapy
AssigneeMati Therapeutics Inc.
InventorsEugene de Juan, Jr., Cary Reich, Stephen Boyd, Hanson S. Gifford, Mark Deem, Alan Rapacki
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Abstract
An implant for insertion through a punctum and into a canalicular lumen of a patient. The implant includes a matrix of material, a therapeutic agent dispersed in the matrix of material, a sheath disposed over a portion of the matrix of material and configured to inhibit the therapeutic agent from being released from the matrix of material into the canalicular lumen and to allow the therapeutic agent to be released from a surface of the matrix of material to a tear film, and a retention structure configured to retain the implant within the canalicular lumen.
Claims20
A drug delivery system for insertion into a lacrimal canaliculus of a patient, comprising:
- a drug supply matrix comprising a therapeutic agent and a hydrogel polymer comprising polyethylene oxide, wherein the drug supply matrix is a cylindrical rod.
A drug delivery system for insertion into a lacrimal canaliculus of a patient, comprising:
- a drug supply matrix comprising a therapeutic agent and a hydrogel polymer comprising polyethylene oxide, wherein the therapeutic agent is selected from an anti-glaucoma agent, a corticosteroid an anti-microbial agent, an anti-allergy agent or a non-steroidal anti-inflammatory agent, and wherein the drug supply matrix is a cylindrical rod.
Dependencies are inferred from the claim text.