Rotating separator, irrigator microcatheter for thrombectomy

A method for removing a blockage in a blood vessel comprising:

• (a) introducing a first endovascular device into a blood vessel of a patient with a blocked blood vessel, the first endovascular device comprising:
• a tube adapted to irrigate a blood vessel during thrombectomy comprising a proximal end, a wall that comprises a circumference and that spans from the proximal end to a distal end, wherein
• the wall of the tube defines a luminal space, a first opening at the proximal end of the tube, and a second opening at the distal end of the tube;
• the wall of the tube comprises one or more side holes around the circumference of the distal end of the tube, wherein the side holes are oriented at an angle relative to the second opening at the distal end of the tube;
• the side holes are located along a length of from 0.1 cm to 60 cm along the distal end of the tube;
• and
• the tube is adapted to receive fluid from the first opening at the proximal end of the tube and to eject fluid from the second opening and side holes at the distal end of the tube;
• (b) advancing the first endovascular device to the site of the blockage in the blood vessel of the patient;
• and
• (c) irrigating the blockage by ejecting fluid from the one or more side holes around the circumference of the distal end of the tube;
• (d) introducing a second endovascular device into a blood vessel of the patient having a blocked blood vessel, the second endovascular device comprising:
• an aspiration catheter comprising a proximal end, a wall that comprises a circumference and that spans the proximal end to a distal end, wherein the wall of the aspiration catheter defines a luminal space, a first opening at the proximal end of the aspiration catheter and a second opening at the distal end of the aspiration catheter;
• and a flared, semi-permeable filter adapted to allow passage of blood cells and serum and to capture emboli, the semi-permeable filter connected to the distal end of the aspiration catheter;
• wherein the semi-permeable filter comprises a shape and attachment to the aspiration catheter that directs emboli toward the second opening of the aspiration catheter for removal of emboli through the luminal space of the aspiration catheter;
• (e) advancing the second endovascular device to a blood vessel that receives blood from the site of the blocked blood vessel;
• (f) aspirating the blockage with the aspiration catheter;
• (g) rotating the first endovascular device around its axis, the first endovascular device further comprising:
• at least one microwire comprising a first end and a second end, wherein each of the first end and second end are connected to the first endovascular device;
• and a plurality of cross strut wires, wherein each cross-strut wire comprises a first end and a second end, the first end of each cross-strut wire connected to the first endovascular device and the second end of each cross-strut wire connected to the at least one microwire;
• wherein the first endovascular device is adapted to rotate around its axis so that one or more half-loop structures attached to the device rotate around the axis of the first endovascular device and is/are effective to macerate an obstruction during thrombectomy;
• and (h) capturing with the semi-permeable filter and removing by aspiration emboli that have traveled from the site of the blockage to the second endovascular device;
• wherein the second endovascular device is effective to prevent emboli from causing further blockage of blood vessels in the patient” after “(c) irrigating the blockage by ejecting fluid from the one or more side holes around the circumference of the distal end of the tube.