Method of noninvasive measurement of blood glucose concentrations and apparatus for the implementation thereof

A method for non-invasive measurement of glucose concentration in human blood, comprising:

• exposing a biological object supplied with blood and capable of transmitting infrared radiation therethrough, to an incident beam of polarized infrared radiation with a given angular position of a polarization plane;
• dividing the radiation transmitted through the biological object into a first part and a second part, the second part being directed to a polarizer-analyzer;
• determining an angular position of a polarization plane of the radiation transmitted through the biological object with the polarizer-analyzer;
• measuring an angle shift between said angular positions of the polarization planes of the incident and transmitted radiation;
• and
• calculating a glucose concentration C by the following formula:
• C=ƒ(α),
• where
• α is the angle shift, and
• ƒ is a function determinable for each individual by a calibration at several specific values of glucose concentration in blood measured by an absolute invasive method;
• wherein for determining said angular position of the polarization plane of the radiation transmitted through the biological object, the method further includes:
• executing angular oscillations of the polarizer-analyzer around an axis parallel to that of the incident beam;
• performing multiple measurements of the functions of a physical quantity dependent on instantaneous values of the infrared radiation intensity transmitted through the polarizer-analyzer versus instantaneous values of the angular positions of the polarizer-analyzer in the course of execution of said angular oscillations, said physical quantity being a difference between the intensity of said first part of the radiation and said intensity of the radiation transmitted through the polarizer-analyzer;
• determination of extrema of said functions;
• and
• calculation of said angle shift as a parameter of said extrema distribution.