Container system for tissue stabilization for molecular and histopathology diagnostics

A system for storing and preserving a biological sample, comprising:

• a first container having a closed end, an open end, and a sidewall extending between the closed end and the open end defining a first container interior;
• a second container having a closed end, an open end, and a sidewall extending between the closed end and the open end defining a second container interior;
• a first closure for enclosing the open end of the first container, wherein the first closure has a bottom surface detachably connectable to a sample holder having an internal cavity configured for holding a biological sample;
• and
• a second closure for enclosing the open end of the second container,
• wherein the first closure is adapted to dispose the sample holder within the first container interior when the first closure encloses the open end of the first container, and the first closure is adapted to subsequently dispose the sample holder within the second container interior when the first closure encloses the open end of the second container,
• wherein the first closure is rotatable with respect to the sample holder when the sample holder is connected to the first closure and when the first closure encloses the open end of the first container or the second container such that an orientation of the sample holder remains substantially fixed relative to the first container or the second container during rotation of the first closure relative to the first container or the second container, and
• wherein the sample holder comprises a closable housing comprising a plurality of fluid openings adapted for allowing fluid contained within at least one of the first container and the second container to pass into the internal cavity.