Methods for producing biological materials
AssigneePalo Alto Investors
InventorAnthony Joonkyoo Yun
Life of this patent
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Abstract
Methods of producing biological materials from cells and organisms are provided. Aspects of the methods include modulating the stress conditions of the cells and/or organism to produce biological materials having one or more desired properties. In certain aspects, the cell or organism is evaluated to detect the presence or absence of a stressed phenotype, wherein an unstressed phenotype may be produced before the cell or organism produces the biological material of interest. The biological materials produced from such cells and organisms may be used for a variety of applications, including therapeutic, research, and other applications.
Claims12
A method for producing a biological product, the method comprising:
- evaluating a multicellular organism to identify the presence or absence of an unstressed phenotype;
- extracting a plurality of cells from the organism;
- introducing nucleic acid encoding at least a portion of the biological product into the plurality of cells;
- culturing the cells under conditions allowing for expression of the biological product;
- and
- recovering the biological product,
- wherein the biological product produced in a cell derived from an organism having an unstressed phenotype is different from the biological product in a cell derived from an organism not having a stressed phenotype.
Dependencies are inferred from the claim text.