Biosynthesis of phenylpropanoids and phenylpropanoid derivatives
AssigneeEvolva SA
InventorsErnesto Simon Vecilla, Beata Joanna Lehka, Carlos Casado Vazquez
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Abstract
Provided herein are recombinant hosts and methods for producing phenylpropanoid and phenylpropanoid derivative compounds. It was found that tyrosine ammonia lyase from Aeromonas salmonicida A449 provides improved coumaric acid production.
Claims29
A recombinant host comprising a recombinant gene encoding a tyrosine ammonia lyase (TAL) polypeptide, wherein the host is capable of producing a phenylpropanoid or a phenylpropanoid derivative compound, and wherein the TAL polypeptide sequence has at least 90% identity to the amino acid sequence set forth in SEQ ID NO:31, and uses tyrosine as a preferred substrate.
Dependencies are inferred from the claim text.