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US 10,294,449 B2Granted
Fiber scaffolds for enhancing cell proliferation in cell culture
AssigneeNanofiber Solutions, LLC
InventorJed K. Johnson
Life of this patent
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Abstract
A substrate for culturing cells that includes at least one fiber scaffold adapted to be contained within a disposable or non-disposable bioreactor, wherein the fiber scaffold further includes polymer fibers that have been created by electrospinning, and wherein the orientation of the fibers in the scaffold relative to one another is generally parallel, random, or both.
Claims16
A container comprising:
- a bioreactor bag having an exterior surface and an interior surface;
- and
- a fiber scaffold contained within the bioreactor bag, the fiber scaffold comprising an electro-spun blend of polyethylene terephthalate and polyurethane polymer fibers having an orientation relative to one another that is generally parallel, random, or a combination thereof;
- wherein the electro-spun blend of polyethylene terephthalate and polyurethane polymer fibers has a weight ratio of about 2:8 polyethylene terephthalate to polyurethane.
1 more element
A container comprising:
- a bioreactor bag having an exterior surface and an interior surface;
- and
- a plurality of fiber scaffolds contained within the bioreactor bag, each fiber scaffold comprising an electro-spun blend of polyethylene terephthalate and polyurethane polymer fibers having an orientation relative to one another that is generally parallel, random, or a combination thereof;
- wherein the electro-spun blend of polyethylene terephthalate and polyurethane polymer fibers has a weight ratio of about 2:8 polyethylene terephthalate to polyurethane.
1 more element
Dependencies are inferred from the claim text.