Tetracyclic anthraquinone derivatives

A method for treating-tumor and/or cancer, comprising administering to a subject in need thereof a therapeutically effective amount of a compound represented by formula (I) or a pharmaceutically acceptable salt thereof, or a formulation comprising a compound represented by formula (I) or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier,

• wherein:
• R1 is selected from the group consisting of H, optionally substituted alkyl, and optionally substituted alkoxy;
• R2 is selected from the group consisting of H, optionally substituted aryl, optionally substituted heteroaryl, optionally substituted (alkyleneoxy)malkyl, optionally substituted heterocyclyl, optionally substituted alkyl, and optionally substituted —S(═O)2R;
• R3 is selected from the group consisting of H, optionally substituted aryl, optionally substituted heteroaryl, optionally substituted (alkyleneoxy)malkyl, optionally substituted heterocyclyl, optionally substituted alkyl, and optionally substituted —S(═O)2R;
• or NR2R3 represents optionally substituted heterocyclyl;
• wherein R comprises optionally substituted alkyl, optionally substituted cyclohydrocarbyl, optionally substituted heterocyclyl, optionally substituted aryl, or optionally substituted heteroaryl;
• m is selected from the group consisting of 0, 23, 2, 3, 4, 5, 6, 7, 8, 9, 10, and 11;
• W is selected from the group consisting of O and NH;
• R4 is selected from the group consisting of H, F, and optionally substituted alkyl;
• R5 is selected from the group consisting of H, F, optionally substituted alkyl and OR6, wherein R6 is selected from the group consisting of H and tetrahydropyran-2-yl;
• and
• n is selected from the group consisting of 23, 2 and 3;
• wherein the tumor and/or cancer is selected from the group consisting of gastric cancer, intestine cancer, head and neck cancer, cervical cancer, brain glioma, various leukemia, lymphoma, and multiple bone marrow cancer.