Compounds

A compound which is selected from the following:

• Compound
• No:
• Structure
• 109
• 105
• 112
• 503
• 506
• 518
• 519
• 526
• 533
• 540
• 543
• 553
• 565
• 584
• and pharmaceutically acceptable salts thereof.

A compound of formula (II), or a pharmaceutically acceptable salt thereof,

• wherein:
• X is selected from amino, alkylamino, arylamino, hydroxyl, alkoxy and aryloxy;
• L is an alkylene linker group having from 1 to 6 carbon atoms, wherein said alkylene linker group is optionally substituted by one or more R″ groups;
• Z is a piperidinyl or piperazinyl group that is optionally substituted by one or more groups selected from R″ and (CH2)mNR11R12;
• Y is an aryl or heteroaryl group, wherein said aryl or heteroaryl group is optionally substituted by one or more groups selected from halo, OR13, alkyl, aryl, alkenyl, alkynyl, NHCO2R4, NHCONR5R6, NHCOR7, NH-alkyl, NH-alkenyl, NH(CH2)n-aryl, (CH2)p-heteroaryl, (CH2)qCO2R8, (CH2)rCOR9 and NHSO2R10, wherein each alkyl, alkenyl, aryl or heteroaryl moiety in the aforementioned list is optionally further substituted by one or more groups selected from alkyl, halo, OH, NH2, alkoxy, aryloxy, alkylamino, arylamino, carboxyl and carboxamide;
• R′ is selected from H, alkyl, aryl, heteroaryl and halo, wherein said alkyl, aryl and heteroaryl groups may be optionally substituted by one or more R″ groups;
• R4 to R10 and R13 are each independently selected from alkyl, alkenyl and aryl;
• and
• n, m, p, q and r are each independently selected from 0, 1, 2, 3, 4, 5 and 6;
• each R″ is independently selected from alkyl, OH, alkoxy and halo;
• R11 and R12 are each independently selected from alkyl and alkenyl;
• or R11 and R12 are linked together with the nitrogen to which they are attached to form a heterocycloalkyl or heterocycloalkenyl group;
• for use in treating a disorder selected from Alzheimer's disease, Epstein Barr Virus and Dengue fever.