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US 10,293,074 B2Granted
Wound dressing materials
AssigneeKCI USA, Inc.
InventorLorraine Nisbet
Life of this patent
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Abstract
A wound dressing material comprising: a wound dressing carrier, N-acetyl cysteine or a salt or derivative thereof, and a stabilized ascorbate. Suitably, the stabilized ascorbate comprises an ascorbate-2-polyphosphate. Also provided are wound dressings comprising the materials, methods of treatment with the materials, and methods of making the materials.
Claims13
A wound dressing, comprising:
- an active layer comprising a wound-facing side, N-acetyl cysteine or a salt thereof, and a stabilized ascorbate, wherein a weight ratio of N-acetyl cysteine or a salt thereof to the stabilized ascorbate is from about 1:4 to about 4:1;
- a backing sheet extending over the active layer opposite to the wound facing side;
- and
- a moisture-vapor transmitting adhesive layer disposed between the backing sheet and the active layer;
- wherein the stabilized ascorbate comprises a member selected from the group consisting of ascorbate 2-phosphate or polyphosphate compounds, trisodium L-ascorbyl-2-monophosphate, 2-phospho-L-ascorbic acid trisodium salt, magnesium ascorbyl phosphate (MAP), L-ascorbic acid mono(dihydrogen phosphate) magnesium salt, magnesium L-ascorbic acid-2-phosphate, trisodium L-ascorbyl-2-polyphosphate, and a combination of any two or more thereof.
2 more elements
Dependencies are inferred from the claim text.